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Bupivacaine

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Local Infiltration Analgesia With Liposomal Bupivacaine Improves Early Outcomes After Total Knee Arthroplasty: 24-Hour Data From the PILLAR Study.

The Journal of arthroplasty 30799269
BACKGROUND: Enhanced postoperative care pathways have shifted total knee arthroplasty (TKA) to outpatient and short-stay settings, placing greater emphasis on predischarge outcomes. In this study, we report prespecified secondary and tertiary end poi...
Aged Aged, 80 and over Analgesia Analgesics, Opioid Anesthetics, Local Arthroplasty, Replacement, Knee Bupivacaine Double-Blind Method Female Humans Male Middle Aged Pain Management Pain, Postoperative
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Effects of hyaluronidase on ropivacaine or bupivacaine regional anaesthesia of the canine pelvic limb.

Veterinary anaesthesia and analgesia 30718077
OBJECTIVE: To determine the effect of hyaluronidase on time to onset and offset of anaesthesia in ropivacaine or bupivacaine femoral-ischiatic nerve blocks.
Anesthetics, Local Animals Bupivacaine Dogs Female Femoral Nerve Hindlimb Hyaluronoglucosaminidase Male Nerve Block Pain Measurement Random Allocation Ropivacaine Treatment Outcome
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Neurotoxicity of intraneural injection of bupivacaine liposome injectable suspension versus bupivacaine hydrochloride in a porcine model.

Veterinary anaesthesia and analgesia 30711466
OBJECTIVE: To test whether neurotoxic effects of a bupivacaine liposome injectable suspension differ from those of a standard formulation of bupivacaine hydrochloride (HCl) after intraneural injection into the sciatic nerves in pigs.
Anesthetics, Local Animals Bupivacaine Drug Compounding Female Injections Liposomes Male Models, Animal Prospective Studies Random Allocation Sciatic Nerve Swine
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Effectiveness of continuous wound infusion of local anesthetics after abdominal surgeries.

The Journal of surgical research 28550928
BACKGROUND: To assess the effectiveness of continuous preperitoneal wound infusion of local anesthetic drug bupivacaine in providing pain relief, reducing opioid consumption, and enhancing postoperative recovery.
Abdomen Adolescent Adult Aged Aged, 80 and over Analgesics, Opioid Anesthetics, Local Bupivacaine Double-Blind Method Drug Administration Schedule Drug Therapy, Combination Female Follow-Up Studies Humans Infusions, Intralesional Infusions, Parenteral Male Middle Aged Morphine Pain Measurement Pain, Postoperative Prospective Studies Treatment Outcome Young Adult
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A Randomized Controlled Trial Study on the Effect of Adding Dexmedetomidine to Bupivacaine in Supraclavicular Block Using Ultrasound Guidance.

Ethiopian journal of health sciences 28450772
BACKGROUND: The benefits of regional anesthetic techniques are well established. Use of additives to local anesthetics can prolong these benefits. The aim of this study was to find out the effect of adding dexmedetomidine to bupivacaine for supraclav...
Adult Analgesia Analgesics, Non-Narcotic Anesthetics, Local Brachial Plexus Block Bupivacaine Dexmedetomidine Double-Blind Method Drug Therapy, Combination Female Hemodynamics Humans Male Middle Aged Time Factors
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Comparison of ropivacaine with and without fentanyl vs bupivacaine with fentanyl for postoperative epidural analgesia in bilateral total knee replacement surgery.

Journal of clinical anesthesia 28235533
STUDY OBJECTIVES: Pain after total knee replacement (TKR) interferes with early rehabilitation. Although the use of epidural bupivacaine in post-TKR patients is associated with effective analgesia, the associated motor blockade effect delays function...
Aged Amides Analgesia, Epidural Analgesia, Patient-Controlled Analgesics, Opioid Anesthetics, Local Arthroplasty, Replacement, Knee Bupivacaine Double-Blind Method Drug Combinations Female Fentanyl Humans Male Middle Aged Nausea Osteoarthritis Pain Management Pain Measurement Pain, Postoperative Patient Satisfaction Postoperative Care Prospective Studies Ropivacaine Treatment Outcome
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Pharmacodynamics and Pharmacokinetics of Levobupivacaine Used for Epidural Anesthesia in Patients with Liver Dysfunction.

Cell biochemistry and biophysics 27259315
The objective of this study was to study the pharmacodynamics and pharmacokinetics of levobupivacaine used for epidural anesthesia in patients with liver dysfunction. Twenty patients aged 20-60, American Society of Anesthesiologists (ASA) graded I-II...
Adult Anesthesia, Epidural Anesthetics, Local Bupivacaine Female Humans Levobupivacaine Liver Diseases Male Metabolic Clearance Rate Middle Aged Sensation Spinal Nerves Tissue Distribution
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[ED50 of Intrathecal Isobaric Bupivacaine with Epidural Volume Extension for Cesarean Delivery].

Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 26867336
OBJECTIVE: To determine the 50% effective dose (ED50) of intrathecal isobaric bupivacaine in combined spinal-epidural anaesthesia with epidural volume extension for caesarean surgery.
Anesthesia, Epidural Anesthesia, Spinal Anesthetics, Local Bupivacaine Cesarean Section Double-Blind Method Female Humans Logistic Models Pregnancy Prospective Studies Sodium Chloride
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The effect of tramadol and tramadol + gabapentin combination in patients with lumbar disc herniation after epidural steroid injection.

Turkish journal of medical sciences 26775373
BACKGROUND/AIM: To compare the effects of tramadol-only treatment and tramadol + gabapentin treatment in patients who had received an epidural steroid injection.
Administration, Oral Adult Amines Analgesics Anesthetics, Local Bupivacaine Cyclohexanecarboxylic Acids Disability Evaluation Drug Therapy, Combination Female Gabapentin gamma-Aminobutyric Acid Glucocorticoids Humans Injections, Epidural Intervertebral Disc Displacement Low Back Pain Lumbar Vertebrae Male Middle Aged Prospective Studies Single-Blind Method Tramadol Triamcinolone Acetonide Visual Analog Scale
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Ultrasound-guided subcostal transversus abdominis plane infiltration with liposomal bupivacaine for patients undergoing robotic-assisted hysterectomy: a retrospective study.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 25790044
OBJECTIVE: We sought to determine the effect of a subcostal transversus abdominis plane (TAP) block with liposomal bupivacaine on postoperative maximal pain score and length of hospital stay among women undergoing robotic-assisted hysterectomy.
Abdominal Muscles Anesthetics, Local Bupivacaine Female Follow-Up Studies Humans Hysterectomy Laparoscopy Length of Stay Liposomes Middle Aged Nerve Block Pain, Postoperative Prognosis Retrospective Studies Robotics Ultrasonography, Interventional
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