BACKGROUND: Non-small-cell lung cancer (NSCLC) and its surgery significantly increase the venous thromboembolism (VTE) risk. This study explored the VTE risk factors and established a machine-learning model to predict a failure of postoperative throm...
Immunotherapy and chemoimmunotherapy are standard treatments for non-oncogene-addicted advanced non-small cell lung cancer (NSCLC). Currently, a limited number of biomarkers, including programmed death-ligand 1 (PD-L1) expression, microsatellite inst...
International journal of radiation oncology, biology, physics
Mar 13, 2025
PURPOSE: Patients with identical stages or similar tumor volumes can vary significantly in their responses to radiation therapy (RT) due to individual characteristics, making personalized RT for non-small cell lung cancer (NSCLC) challenging. This st...
OBJECTIVES: To extract intratumoral, peritumoral, and integrated intratumoral-peritumoral CT radiomic features, develop multi-source radiomic models using various machine learning algorithms to identify the optimal model, and integrate clinical facto...
Cancer imaging : the official publication of the International Cancer Imaging Society
Mar 12, 2025
PURPOSE: This study aimed to select robust features against lung motion in a phantom study and use them as input to feature selection algorithms and machine learning classifiers in a clinical study to predict the lymphovascular invasion (LVI) of non-...
PURPOSE: To comprehensively analyze the association between preoperative maximum standardized uptake value (SUV) on 18F-fluorodeoxyglucose positron emission tomography-computed tomography and postoperative recurrence in resected non-small cell lung c...
Predictive biomarker identification in cancer treatment has traditionally relied on pre-defined analyses, limiting discoveries to expected biomarkers and potentially overlooking novel ones predictive of therapy response. In this work, we develop a no...
BACKGROUND: Immune checkpoint inhibitors (CPIs) have revolutionized cancer therapy for several tumor indications. However, a substantial fraction of patients treated with CPIs derive no benefit or have short-lived responses to CPI therapy. Identifyin...
AIM: This study evaluates the comparative effectiveness of pathologists versus artificial intelligence (AI) algorithms in scoring PD-L1 expression in non-small cell lung carcinoma (NSCLC). Immune-checkpoint inhibitors have revolutionized NSCLC treatm...
This study aims to apply a multi-modal approach of the deep learning method for survival prediction in patients with non-small-cell lung cancer (NSCLC) using CT-based radiomics. We utilized two public data sets from the Cancer Imaging Archive (TCIA) ...
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