IEEE transactions on image processing : a publication of the IEEE Signal Processing Society
Oct 22, 2018
Breast cancer is found to be the most pervasive type of cancer among women. Computer aided detection and diagnosis of cancer at the initial stages can increase the chances of recovery and thus reduce the mortality rate through timely prognosis and ad...
BACKGROUND: The average sensitivity of conventional cytology for the identification of cancer cells in effusion specimens is only approximately 58%. DNA image cytometry (DNA-ICM), which exploits the DNA content of morphologically suspicious nuclei me...
Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Sep 17, 2018
BACKGROUND: Deep convolutional neural networks have become a widespread tool for the detection of nuclei in histopathology images. Many implementations share a basic approach that includes generation of an intermediate map indicating the presence of ...
BACKGROUND: Nuclear segmentation is an important step for profiling aberrant regions of histology sections. If nuclear segmentation can be resolved, then new biomarkers of nuclear phenotypes and their organization can be predicted for the application...
IEEE transactions on image processing : a publication of the IEEE Signal Processing Society
Jul 18, 2018
In this paper, we propose a novel contour-seed pairs learning-based framework for robust and automated cell/nucleus segmentation. Automated granular object segmentation in microscopy images has significant clinical importance for pathology grading of...
IEEE journal of biomedical and health informatics
Jul 3, 2018
The level set based deformable models (LDM) are commonly used for medical image segmentation. However, they rely on a handcrafted curve evolution velocity that needs to be adapted for each segmentation task. The Convolutional Neural Networks (CNN) ad...
BACKGROUND: Gene-expression companion diagnostic tests, such as the Oncotype DX test, assess the risk of early stage Estrogen receptor (ER) positive (+) breast cancers, and guide clinicians in the decision of whether or not to use chemotherapy. Howev...
Peripheral Blood Smear analysis plays a vital role in diagnosis of many diseases such as leukemia, anemia, malaria, lymphoma and infections. Unusual variations in color, shape and size of blood cells indicate abnormal condition. We used a total of 11...
IEEE journal of biomedical and health informatics
Feb 8, 2018
Due to the importance of nuclear structure in cancer diagnosis, several predictive models have been described for diagnosing a wide variety of cancers based on nuclear morphology. In many computer-aided diagnosis (CAD) systems, cancer detection tasks...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
Dec 28, 2017
The noninvasive, fast acquisition of quantitative phase maps using digital holographic microscopy (DHM) allows tracking of rapid cellular motility on transparent substrates. On two-dimensional surfaces in vitro, MDA-MB-231 cancer cells assume several...