AIMC Topic: Chondrocytes

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Protective Effects of Garlic-Derived S-Allylmercaptocysteine on IL-1-Stimulated Chondrocytes by Regulation of MMPs/TIMP-1 Ratio and Type II Collagen Expression via Suppression of NF-B Pathway.

BioMed research international Dec 3, 2017
BACKGROUND: Garlic-derived S-allylmercaptocysteine (SAMC) has widely been used in many disease therapies. However, the potential effects and mechanism of SAMC on IL-1-stimulated chondrocytes are unclear.
Matrix Metalloproteinases Interleukin-1beta Transcription Factor RelA Gene Expression Osteoarthritis Tumor Necrosis Factor-alpha Collagen Type II NF-kappa B Cysteine Signal Transduction Humans Tissue Inhibitor of Metalloproteinase-1 Chondrocytes Garlic
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Achyranthes bidentate saponins protect rat articular chondrocytes against interleukin-1β-induced inflammation and apoptosis in vitro.

The Kaohsiung journal of medical sciences Dec 30, 2016
Achyranthes bidentate Blume (Niuxi) is often employed for treatment of arthritis in Traditional Chinese Medicine and possesses anti-inflammatory properties. Phytochemical and pharmacological studies proved the oleanane-type saponins to be the main bi...
Achyranthes bcl-Associated Death Protein Matrix Metalloproteinase 3 Primary Cell Culture bcl-X Protein Rats Gene Expression Regulation Inflammation Proliferating Cell Nuclear Antigen Signal Transduction Rats, Sprague-Dawley Cyclooxygenase 2 Male Cartilage, Articular Plant Extracts Saponins Animals Tumor Suppressor Protein p53 Chondrocytes Interleukin-1beta NF-kappa B Anti-Inflammatory Agents, Non-Steroidal Apoptosis Matrix Metalloproteinase 9 Plant Roots Caspase 3 bcl-2-Associated X Protein
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Non-destructive assessment of tissue engineered cartilage maturity using visible and near infrared spectroscopy combined with machine learning.

Biosensors & bioelectronics Oct 15, 2025
Tissue engineering is a promising approach to address the unmet clinical need for treating cartilage damage. Monitoring the characteristics of tissue-engineered cartilage constructs (TECs) during culture is critical for optimizing culture conditions ...
Biosensing Techniques DNA Spectroscopy, Near-Infrared Cattle Cartilage Tissue Engineering Chondrocytes Glycosaminoglycans Humans Machine Learning Animals
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Deep Learning for Chondrocyte Identification in Automated Histological Analysis of Articular Cartilage.

The Iowa orthopaedic journal Jan 1, 2019
BACKGROUND: Histology-based methods are commonly used in osteoarthritis (OA) research because they provide detailed information about cartilage health at the cellular and tissue level. Computer-based cartilage scoring systems have previously been dev...
Deep Learning Image Processing, Computer-Assisted Humans Cartilage, Articular Osteoarthritis Pattern Recognition, Automated Chondrocytes
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