AIMC Topic: Chondrocytes

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Achyranthes bidentate saponins protect rat articular chondrocytes against interleukin-1β-induced inflammation and apoptosis in vitro.

The Kaohsiung journal of medical sciences Dec 30, 2016
Achyranthes bidentate Blume (Niuxi) is often employed for treatment of arthritis in Traditional Chinese Medicine and possesses anti-inflammatory properties. Phytochemical and pharmacological studies proved the oleanane-type saponins to be the main bi...
Animals Male Plant Extracts Rats Inflammation Signal Transduction Rats, Sprague-Dawley Apoptosis Caspase 3 Anti-Inflammatory Agents, Non-Steroidal Plant Roots Interleukin-1beta NF-kappa B Matrix Metalloproteinase 9 bcl-2-Associated X Protein Chondrocytes Saponins Tumor Suppressor Protein p53 Gene Expression Regulation Proliferating Cell Nuclear Antigen Cyclooxygenase 2 Cartilage, Articular Matrix Metalloproteinase 3 Primary Cell Culture Achyranthes bcl-Associated Death Protein bcl-X Protein
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Non-destructive assessment of tissue engineered cartilage maturity using visible and near infrared spectroscopy combined with machine learning.

Biosensors & bioelectronics Oct 15, 2025
Tissue engineering is a promising approach to address the unmet clinical need for treating cartilage damage. Monitoring the characteristics of tissue-engineered cartilage constructs (TECs) during culture is critical for optimizing culture conditions ...
Humans Machine Learning Animals Spectroscopy, Near-Infrared Cattle Biosensing Techniques DNA Chondrocytes Glycosaminoglycans Cartilage Tissue Engineering
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Deep Learning for Chondrocyte Identification in Automated Histological Analysis of Articular Cartilage.

The Iowa orthopaedic journal Jan 1, 2019
BACKGROUND: Histology-based methods are commonly used in osteoarthritis (OA) research because they provide detailed information about cartilage health at the cellular and tissue level. Computer-based cartilage scoring systems have previously been dev...
Humans Deep Learning Image Processing, Computer-Assisted Chondrocytes Osteoarthritis Pattern Recognition, Automated Cartilage, Articular
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