AIMC Topic: Matrix Metalloproteinase 3

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Analysis of diagnostic genes and molecular mechanisms of Crohn's disease and colon cancer based on machine learning algorithms.

Scientific reports Dec 30, 2024
Crohn's disease (CD) is a chronic inflammatory bowel condition, and colon adenocarcinoma (COAD), as one of the most prevalent malignant tumors of the digestive tract, has been indicated by research to have a close association with CD. This study empl...
Computational Biology Gene Expression Regulation, Neoplastic Protein Interaction Maps Gene Regulatory Networks Crohn Disease Colonic Neoplasms Matrix Metalloproteinase 3 Adenocarcinoma Databases, Genetic Algorithms Biomarkers, Tumor Gene Expression Profiling Humans ROC Curve Machine Learning
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Achyranthes bidentate saponins protect rat articular chondrocytes against interleukin-1β-induced inflammation and apoptosis in vitro.

The Kaohsiung journal of medical sciences Dec 30, 2016
Achyranthes bidentate Blume (Niuxi) is often employed for treatment of arthritis in Traditional Chinese Medicine and possesses anti-inflammatory properties. Phytochemical and pharmacological studies proved the oleanane-type saponins to be the main bi...
Gene Expression Regulation Proliferating Cell Nuclear Antigen Saponins Tumor Suppressor Protein p53 Matrix Metalloproteinase 3 Primary Cell Culture Achyranthes Cyclooxygenase 2 Cartilage, Articular NF-kappa B Matrix Metalloproteinase 9 bcl-2-Associated X Protein Chondrocytes Plant Roots Interleukin-1beta Caspase 3 Rats Anti-Inflammatory Agents, Non-Steroidal Inflammation Rats, Sprague-Dawley Male Apoptosis Plant Extracts Signal Transduction Animals bcl-Associated Death Protein bcl-X Protein
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Cytokine and metalloproteinases in gingival fluid from patients with chronic periodontitis.

Investigacion clinica Jun 1, 2016
The purpose of the present research was to determine the levels of IL- 1a, IL- 1 P, TNF-a, IL-6, IL-6sR, IL-8, IL-10, MMP-3 and EMP-8 in gingival crevicular fluid (GCF) of subjects with chronic periodontitis. Clinical measurements were carried out in...
Matrix Metalloproteinase 8 Male Female Gingival Crevicular Fluid Humans Adult Matrix Metalloproteinase 3 Chronic Periodontitis Cytokines
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[Prophylactic administration of all-trans retinoic acid alleviates inflammation in rats with collagen-induced arthritis].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University Feb 20, 2016
OBJECTIVE: To investigate the effects of prophylactic administration of all-trans retinoic acid (ATRA) in relieving inflammation in a rat model of collagen-induced arthritis (CIA).
Collagen Type II Freund's Adjuvant Tumor Necrosis Factor-alpha Tretinoin Female Matrix Metalloproteinase 3 Rats, Wistar Interleukin-10 Th17 Cells Animals Lipids ADAMTS4 Protein Rats Arthritis, Experimental Interleukin-17 T-Lymphocytes, Regulatory Inflammation
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