AIMC Topic: Chromatography, Affinity
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Collaborative Internal Cavity Effect and Interfacial Modulation Mechanism for Boosting Deep Learning-Powered Immunochromatographic Pathogen Detection.
Analytical chemistry
Jul 15, 2025
Nanoenabled immunochromatographic assay (ICA) emerges as a powerful tool for pathogen diagnosis, yet current nanotechnologies are still constrained by inadequate light-matter interaction efficiency, sluggish nanomaterial flow dynamics, and inefficien...
Dual-Channel Catalytic Immunochromatography Empowered by Machine Learning: Ultrasensitive Detection of O157:H7 via Magnetic CoFeO@HRP Nanocomposites.
Analytical chemistry
Jul 2, 2025
Traditional immunochromatographic test strips face significant limitations in detecting trace levels of O157:H7 due to insufficient sensitivity and reliability. To address this challenge, we developed a novel "three-In-One" nanoplatform based on mag...
A smartphone-integrated deep learning strategy-assisted rapid detection system for monitoring dual-modal immunochromatographic assay.
Talanta
Oct 14, 2024
This study focuses on the integration of a custom-built and optimally trained YOLO v5 model into a smartphone app developed with Java language. A dual-modal immunochromatographic rapid detection system based on a deep learning strategy for smartphone...
A Fluorescent Immunochromatography Test Strip for the Rapid Identification of SVV and FMDV.
Transboundary and emerging diseases
Aug 12, 2024
Seneca Valley virus (SVV) and foot-and-mouth disease virus (FMDV) belong to the Picornaviridae family, which can cause similar symptoms. After infection, pigs will develop fever; loss of appetite; blister lesions on the skin and mucous membrane of th...
Computer-aided design space identification for screening of protein A affinity chromatography resins.
Journal of chromatography. A
Apr 8, 2024
The rapidly growing market of monoclonal antibodies (mAbs) within the biopharmaceutical industry has incentivised numerous works on the design of more efficient production processes. Protein A affinity chromatography is regarded as one of the best pr...
Aptamer facilitated purification of functional proteins.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Dec 16, 2017
DNA aptamers are attractive capture probes for affinity chromatography since, in contrast to antibodies, they can be chemically synthesized and, in contrast to tag-specific capture probes (such as Nickel-NTA or Glutathione), they can be used for puri...
Use of quantum dot beads-labeled monoclonal antibody to improve the sensitivity of a quantitative and simultaneous immunochromatographic assay for neuron specific enolase and carcinoembryonic antigen.
Talanta
Dec 5, 2016
Detection of multiplex tumor markers was of great importance for cancer diagnosis. Immunochromatographic test strip (ICTS) was the most frequently-used point-of-care detection means. Herein, a convenient and fast method for simultaneous quantitative ...
A robust robotic high-throughput antibody purification platform.
Journal of chromatography. A
May 24, 2016
Monoclonal antibodies (mAbs) have become the fastest growing segment in the drug market with annual sales of more than 40 billion US$ in 2013. The selection of lead candidate molecules involves the generation of large repertoires of antibodies from w...
A competitive immunoassay for ultrasensitive detection of Hg(2+) in water, human serum and urine samples using immunochromatographic test based on surface-enhanced Raman scattering.
Analytica chimica acta
Dec 18, 2015
An immunochromatographic test (ICT) strip was developed for ultrasensitive competitive immunoassay of Hg(2+). This strategy was achieved by combining the easy-operation and rapidity of ICT with the high sensitivity of surface-enhanced Raman scatterin...
[Evaluation of the lateral flow Aspergillus assay for the diagnosis of invasive aspergillosis, experience in a university hospital].
Revista chilena de infectologia : organo oficial de la Sociedad Chilena de Infectologia
Jan 1, 2018
BACKGROUND: The incidence of invasive aspergillosis is increasing. Its diagnosis is based on clinical and microbiological criteria which include the determination of serological markers such as galactomannan. Recently, the Aspergillus lateral flow de...
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