AIMC Topic: Chromatography, High Pressure Liquid

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[Determination of dacarbazine in the urine of mice with melanoma by high performance liquid chromatography].

Se pu = Chinese journal of chromatography
Dacarbazine (DTIC) is a first-line chemotherapy drug that is widely used in clinical practice for malignant melanoma. DTIC is metabolized by the liver . Some drugs are excreted in urine in the form of a prototype. Hence, DTIC in urine can be monitore...

[Determination of -nitrosodimethylamine in metformin hydrochloride and its preparations by high performance liquid chromatography-tandem mass spectrometry].

Se pu = Chinese journal of chromatography
A method was established for the determination of -nitrosodimethylamine (NDMA) in metformin hydrochloride active pharmaceutical ingredient (API) and preparation samples by high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). ...

[Preparation and application of urushiol methacrylate-bonded silica liquid chromatographic stationary phase].

Se pu = Chinese journal of chromatography
A novel stationary phase for high performance liquid chromatography was prepared using urushiol methacrylate as the chromatographic ligand. The mixed urushiol methacrylate was prepared using urushiol and methacryloyl chloride via a substitution react...

Stability and compatibility of methotrexate and dexamethasone in 0.9% sodium chloride for intrathecal injection.

Pakistan journal of pharmaceutical sciences
The stability of a mixture of methotrexate and dexamethasone sodium phosphate in 0.9% sodium chloride for intrathecal (IT) injection was assessed. To simulate the clinically used concentrations of the admixtures, 2mL of 0.9% sodium chloride was added...

[Rapid screening and determination of fentanyl and its analogues in drugs by liquid chromatography- quadrupole time-of-flight mass spectrometry].

Se pu = Chinese journal of chromatography
A method based on liquid chromatography coupled with high-resolution quadrupole time-of-flight mass spectrometry (LC-QTOF-MS) was developed for the simultaneous screening and determination of fentanyl and its 26 analogs in liquid and solid powder dru...

[Simultaneous determination of twelve antiepileptic drugs in serum by ultra high performance liquid chromatography-tandem mass spectrometry].

Se pu = Chinese journal of chromatography
A sensitive, high-throughput method was established for the simultaneous determination of 12 antiepileptics in serum by ultra high performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The antiepileptics were gabapentin, lamotrigin...

[Determination of vitamin K and vitamin K in modulation milk powder by post-column reduction-high performance liquid chromatography].

Se pu = Chinese journal of chromatography
A method for the determination of vitamin K and vitamin K in modulation milk powder was developed by high performance liquid chromatography (HPLC) coupled with post-column reduction. The samples were dissolved in water, lipase hydrolyzed, saponified ...

[Determination of diazepam in aquatic products by ultra performance liquid chromatography-tandem mass spectrometry with pass-through solid phase extraction].

Se pu = Chinese journal of chromatography
A method was developed for the determination of diazepam in aquatic products by pass-through solid phase extraction-ultra performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). The analyte was extracted with acetonitrile directly an...

Integration of ultra-high-pressure liquid chromatography-tandem mass spectrometry with machine learning for identifying fatty acid metabolite biomarkers of ischemic stroke.

Chemical communications (Cambridge, England)
We report for the first time the integration of ultra-high-pressure liquid chromatography-tandem mass spectrometry with machine learning for identifying fatty acid metabolite biomarkers of ischemic stroke. In particular, we develop an optimal model t...

[Simultaneous determination of five baicaleins in healthy product tablets by dispersive solid-phase extraction-high performance liquid chromatography-tandem mass spectrometry].

Se pu = Chinese journal of chromatography
A method based on dispersive solid-phase extraction-high performance liquid chromatography-tandem mass spectrometry (DSPE-HPLC-MS/MS) was developed for the simultaneous determination of five analytes scutellarein, 4'-hydroxywogonin, norwogonin, baica...