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Chronic Disease

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A predictive analytics framework for identifying patients at risk of developing multiple medical complications caused by chronic diseases.

Artificial intelligence in medicine
Chronic diseases often cause several medical complications. This paper aims to predict multiple complications among patients with a chronic disease. The literature uses single-task learning algorithms to predict complications independently and assume...

Prospective evaluation of clarithromycin in recurrent chronic rhinosinusitis with nasal polyps.

Brazilian journal of otorhinolaryngology
INTRODUCTION: The antiinflammatory effects of macrolides, especially clarithromycin, have been described in patients with chronic rhinosinusitis without polyps and also other chronic inflammatory airway diseases. There is no consensus in the literatu...

Common pre-diagnostic features in individuals with different rare diseases represent a key for diagnostic support with computerized pattern recognition?

PloS one
BACKGROUND: Rare diseases (RD) result in a wide variety of clinical presentations, and this creates a significant diagnostic challenge for health care professionals. We hypothesized that there exist a set of consistent and shared phenomena among all ...

From protocolized to person-centered chronic care in general practice: study protocol of an action-based research project (COPILOT).

Primary health care research & development
AIM: To develop a proactive person-centered care approach for persons with (multiple) chronic diseases in general practice, and to explore the impact on 'Quadruple aims': experiences of patients and professionals, patient outcomes and costs of resour...

From Discrete to Continuous Modeling of Lymphocyte Development and Plasticity in Chronic Diseases.

Frontiers in immunology
The molecular events leading to differentiation, development, and plasticity of lymphoid cells have been subject of intense research due to their key roles in multiple pathologies, such as lymphoproliferative disorders, tumor growth maintenance and c...

Unilateral vs Bilateral Hybrid Approaches for Upper Limb Rehabilitation in Chronic Stroke: A Randomized Controlled Trial.

Archives of physical medicine and rehabilitation
OBJECTIVE: To investigate the effects of unilateral hybrid therapy (UHT) and bilateral hybrid therapy (BHT) compared with robot-assisted therapy (RT) alone in patients with chronic stroke.

Unsupervised Learning Techniques for the Investigation of Chronic Rhinosinusitis.

The Annals of otology, rhinology, and laryngology
OBJECTIVES: This article reviews the principles of unsupervised learning, a novel technique which has increasingly been reported as a tool for the investigation of chronic rhinosinusitis (CRS). It represents a paradigm shift from the traditional appr...

Efficacy of Cardiac Rehabilitation with Assistance from Hybrid Assistive Limb in Patients with Chronic Heart Failure: Protocol for a Randomized Controlled Study.

Cardiology
The hybrid assistive limb (HAL) provides motion assistance based on bioelectrical signals detected on the skin surface when muscle forces are generated. The lumbar-type HAL is expected to expand the therapeutic options for severe cardiac patients who...