AIMC Topic: Circadian Rhythm
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Mood Prediction of Patients With Mood Disorders by Machine Learning Using Passive Digital Phenotypes Based on the Circadian Rhythm: Prospective Observational Cohort Study.
Journal of medical Internet research
Apr 17, 2019
BACKGROUND: Virtually, all organisms on Earth have their own circadian rhythm, and humans are no exception. Circadian rhythms are associated with various human states, especially mood disorders, and disturbance of the circadian rhythm is known to be ...
Universal method for robust detection of circadian state from gene expression.
Proceedings of the National Academy of Sciences of the United States of America
Sep 10, 2018
Circadian clocks play a key role in regulating a vast array of biological processes, with significant implications for human health. Accurate assessment of physiological time using transcriptional biomarkers found in human blood can significantly imp...
Phase Relationship between DLMO and Sleep Onset and the Risk of Metabolic Disease among Normal Weight and Overweight/Obese Adults.
Journal of biological rhythms
Dec 20, 2017
Circadian misalignment is hypothesized to contribute to increased diabetes and obesity among shift workers and individuals with late sleep timing. Accordingly, the goal of our study was to identify-among normal and overweight/obese adults-association...
Mechanisms of pulse pressure amplification dipping pattern during sleep time: the SAFAR study.
Journal of the American Society of Hypertension : JASH
Dec 14, 2017
The difference in pulse pressure (PP) between peripheral arteries and the aorta, called pulse pressure amplification (PPamp), is a well-described physiological phenomenon independently associated with cardiovascular events. Recent studies suggest tha...
Identification of human circadian genes based on time course gene expression profiles by using a deep learning method.
Biochimica et biophysica acta. Molecular basis of disease
Dec 12, 2017
Circadian genes express periodically in an approximate 24-h period and the identification and study of these genes can provide deep understanding of the circadian control which plays significant roles in human health. Although many circadian gene ide...
Daily changes of individual gait patterns identified by means of support vector machines.
Gait & posture
Jul 29, 2016
Despite the common knowledge about the individual character of human gait patterns and about their non-repeatability, little is known about their stability, their interactions and their changes over time. Variations of gait patterns are typically des...
Can Lionel Messi's brain slow down time passing?
Chronobiology international
Mar 24, 2016
It seems that seeing others in slow-motion by heroes does not belong only to movies. When Lionel Messi plays football, you can hardly see anything from him that other players cannot do. Then why he is not stoppable really? It seems the answer may be ...
Population pharmacokinetic/pharmacodynamic assessment of pharmacological effect of a selective estrogen receptor β agonist on total testosterone in healthy men.
Clinical pharmacology in drug development
Jun 8, 2015
BACKGROUND: LY500307 is a highly selective estrogen receptor β (ERβ) agonist, which loses its selectivity at high dose and leads to undesirable suppression of total testosterone (TT) concentration. The objective of the present analysis was to define ...
Testosterone
Single-Blind Method
Models, Biological
Circadian Rhythm
Administration, Oral
Cross-Over Studies
Healthy Volunteers
Nonlinear Dynamics
London
Humans
Benzopyrans
Selective Estrogen Receptor Modulators
Biomarkers
Drug Administration Schedule
Estrogen Receptor beta
Young Adult
Fourier Analysis
Adult
Male
Middle Aged
Recognition of activities of daily living in healthy subjects using two ad-hoc classifiers.
Biomedical engineering online
Jun 6, 2015
BACKGROUND: Activities of daily living (ADL) are important for quality of life. They are indicators of cognitive health status and their assessment is a measure of independence in everyday living. ADL are difficult to reliably assess using questionna...
Big data approaches for novel mechanistic insights on sleep and circadian rhythms: a workshop summary.
Sleep
Jun 13, 2025
The National Center on Sleep Disorders Research of the National Heart, Lung, and Blood Institute at the National Institutes of Health hosted a 2-day virtual workshop titled Big Data Approaches for Novel Mechanistic Insights on Disorders of Sleep and ...
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