AIMC Topic: Cohort Studies

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International external validation of the SORG machine learning algorithm for predicting sustained postoperative opioid prescription after anterior cervical discectomy and fusion using a Taiwanese cohort of 1,037 patients.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: Anterior cervical discectomy and fusion (ACDF) is widely performed for cervical spine disorders, with opioids commonly prescribed postoperatively for pain management. However, prolonged opioid use carries significant risks such as...

Prognostic value of SAPS II score for 28-day mortality in ICU patients with acute pulmonary embolism.

International journal of cardiology
BACKGROUND: Acute pulmonary embolism (APE) is a common and life-threatening emergency in intensive care units (ICUs). Effective risk assessment tools are essential to improve patient outcomes. This study aims to evaluate the association between Simpl...

Exploring the Incremental Value of Aorta Enhancement Normalization Method in Evaluating Renal Cell Carcinoma Histological Subtypes: A Multi-center Large Cohort Study.

Academic radiology
RATIONALE AND OBJECTIVES: The classification of renal cell carcinoma (RCC) histological subtypes plays a crucial role in clinical diagnosis. However, traditional image normalization methods often struggle with discrepancies arising from differences i...

Machine learning models for predicting metabolic dysfunction-associated steatotic liver disease prevalence using basic demographic and clinical characteristics.

Journal of translational medicine
BACKGROUND: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a global health concern that necessitates early screening and timely intervention to improve prognosis. The current diagnostic protocols for MASLD involve complex procedu...

Development and evaluation of a machine learning model for osteoporosis risk prediction in Korean women.

BMC women's health
BACKGROUND: The aim of this study was to develop a machine learning (ML) model for classifying osteoporosis in Korean women based on a large-scale population cohort study. This study also aimed to assess ML model performance compared with traditional...

Predicting quality of life of patients after treatment for spinal metastatic disease: development and internal evaluation.

The spine journal : official journal of the North American Spine Society
BACKGROUND CONTEXT: When treating spinal metastases in a palliative setting, maintaining or enhancing quality of life (QoL) is the primary therapeutic objective. Clinicians tailor their treatment strategy by weighing the QoL benefits against expected...

Predicting rheumatoid arthritis progression from seronegative undifferentiated arthritis using machine learning: a deep learning model trained on the KURAMA cohort and externally validated with the ANSWER cohort.

Arthritis research & therapy
BACKGROUND: Undifferentiated arthritis (UA) often develops into rheumatoid arthritis (RA), but predicting disease progression from seronegative UA remains challenging because seronegative RA often does not meet the classification criteria. This study...

Proposed Comprehensive Methodology Integrated with Explainable Artificial Intelligence for Prediction of Possible Biomarkers in Metabolomics Panel of Plasma Samples for Breast Cancer Detection.

Medicina (Kaunas, Lithuania)
: Breast cancer (BC) is the most common type of cancer in women, accounting for more than 30% of new female cancers each year. Although various treatments are available for BC, most cancer-related deaths are due to incurable metastases. Therefore, th...

Development and validation of pan-cancer lesion segmentation AI-model for whole-body 18F-FDG PET/CT in diverse clinical cohorts.

Computers in biology and medicine
BACKGROUND: This study develops a deep learning-based automated lesion segmentation model for whole-body 3DF-fluorodeoxyglucose (FDG)-Position emission tomography (PET) with computed tomography (CT) images agnostic to disease location and site.