AIMC Topic: Colorectal Neoplasms

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Machine learning-based risk modeling for safety-focused learning curve assessment in robotic left-sided colorectal cancer surgery.

Journal of robotic surgery
The transition from laparoscopic to robotic surgery for left-sided colorectal cancer raises safety concerns during the learning curve, particularly when complex cases are preferentially selected for the robotic platform. We evaluated a machine learni...

Radiomics profiling combined with clinical risk factors for preoperative Lymphatic Metastasis prediction in Colorectal cancer: A multicenter study.

PloS one
PURPOSE: Accurate preoperative assessment of regional lymphatic metastases (LNM) is essential for effective surgical selection of patients with colorectal cancer (CRC). This study aimed to develop a machine learning (ML) model that integrates radiomi...

From glycolytic signatures to patients: A translational roadmap for reproducible, equitable deployment of multi-omics and AI in colorectal cancer.

Medical oncology (Northwood, London, England)
Recent advances in Medical Oncology highlight the integration of bulk and single-cell transcriptomics to reveal glycolytic heterogeneity in colorectal cancer. Translating these discoveries into reliable clinical tools requires rigorous methods, trans...

An interpretable machine learning model based on MRI radiomics and GAME score for predicting early recurrence after thermal ablation in colorectal liver metastases.

International journal of colorectal disease
OBJECTIVE: To develop and validate machine learning models based on preoperative magnetic resonance imaging(MRI) and baseline clinical characteristics for predicting early recurrence(ER) in patients with colorectal liver metastases(CRLM) treated with...

Diagnostic performance of eNose technology in detecting colorectal cancer recurrence: A prospective evaluation.

PloS one
INTRODUCTION: After curative treatment for colorectal cancer (CRC), there is a 15% risk of recurrence. Early detection of an asymptomatic recurrence may lead to curative treatment options. To date, follow-up strategies do not have optimal sensitivity...

PGMNet: a polyp segmentation network based on bit-plane slicing and multi-scale adaptive fusion.

Biomedical physics & engineering express
Accurate detection and segmentation of polyps during colonoscopy are of great significance for the early prevention and treatment of colorectal cancer. However, due to the considerable variations in polyp size and shape, as well as their blurred boun...

Development of liquid biopsy for screening colorectal cancer through the combination of an antibody microarray-based metal-enhanced sandwich immunofluorescent assay of cytokines with machine learning.

The Analyst
The simultaneous determination of the expression levels of multiple inflammation-associated cytokines in blood holds great promise for the early screening of cancer including colorectal cancer (CRC). Herein, an antibody microarray-based sandwich meta...

Machine learning-powered single-molecule cancer diagnosis using DNA origami tags.

Science advances
Single-molecule detection (SMD) holds considerable promise in biomedical research. Although atomic force microscopy (AFM) provides an important technique with nanoscale resolution for SMD, its broader application is limited by labeling challenges and...

Similarity-guided swarm of models: enhancing semi-supervised learning in computational pathology.

Scientific reports
High-precision pixel-level annotation has been a major bottleneck in computational pathology due to its time-consuming nature and reliance on expert knowledge. Semi-supervised learning (SSL) provides a promising approach to alleviate this challenge b...

Multi-scale aggregation network for colonoscopic polyp segmentation via frequency domain decoupling.

Scientific reports
Automated segmentation of colorectal polyps is of great significance for early screening and clinical intervention of colorectal cancer. However, the diversity of polyp morphology and the uneven contrast caused by illumination changes in colonoscopy ...