Coronary artery disease (CAD) is a leading cause of death globally. Antiplatelet therapy remains crucial in preventing and treating CAD-associated thrombotic complications, but it concurrently amplifies the risk of bleeding. Unfortunately, traditiona...
BACKGROUND: Vascular smooth muscle cells loaded with cholesterol (foam-VSMCs) play a crucial role in the progression of human atherosclerosis. Exchange Protein Directly Activated by cAMP 1 (EPAC1) is a critical protein in the regulation of vascular t...
The international journal of cardiovascular imaging
Apr 26, 2025
Non-contrast enhanced magnetic resonance coronary angiography (MRCA) is a promising coronary heart disease screening modality. However, its clinical application is hindered by inherent limitations, including low spatial resolution and insufficient co...
BACKGROUND: Abdominal computed tomography (CT) is commonly performed in adults. Abdominal aortic calcification (AAC) can be visualized and quantified using artificial intelligence (AI) on CTs performed for other clinical purposes (opportunistic CT). ...
BACKGROUND: Exclusion of coronary stenosis in individuals with suggestive symptoms is challenging. Cardiac CT or coronary angiography is often used but is inefficient and costly and involves risks. Sex-stratified algorithms based on electronic health...
INTRODUCTION: Percutaneous coronary intervention (PCI) has been the main treatment of coronary artery disease (CAD). In this review, we aimed to compare the performance of machine learning (ML) vs. logistic regression (LR) models in predicting differ...
The international journal of cardiovascular imaging
Apr 22, 2025
In symptomatic patients undergoing coronary CTA for suspected coronary artery disease (CAD), we assessed if quantification of plaque burden, in addition to luminal narrowing and clinical risk factors, offers incremental value for the identification o...
The coronary angiography-derived fractional flow reserve (FFR) curve, referred to as the Angio-FFR curve, is crucial for guiding percutaneous coronary intervention (PCI). The invasive FFR is the diagnostic gold standard for determining functional sig...
INTRODUCTION: About one-third of adults in the USA have some grade of hepatic steatosis. Coronary artery calcium (CAC) scans contain more information than currently reported. We previously reported new artificial intelligence (AI) algorithms applied ...
European journal of nuclear medicine and molecular imaging
Apr 8, 2025
PURPOSE: Deep learning (DL) models for predicting obstructive coronary artery disease (CAD) using myocardial perfusion imaging (MPI) have shown potential for enhancing diagnostic accuracy. However, their ability to maintain consistent performance acr...
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