AIMC Topic: Culture Media

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Toward sustainable culture media: Using artificial intelligence to optimize reduced-serum formulations for cultivated meat.

The Science of the total environment
When considering options for future foods, cell culture approaches are at the fore, however, culture media to support the process has been identified as a significant contributor to the overall global warming potential (GWP) and cost of cultivated me...

Machine learning to predict effective reaction rates in 3D porous media from pore structural features.

Scientific reports
Large discrepancies between well-mixed reaction rates and effective reactions rates estimated under fluid flow conditions have been a major issue for predicting reactive transport in porous media systems. In this study, we introduce a framework that ...

Pump Up the Jam: Granular Media as a Quasi-Hydraulic Fluid for Independent Control Over Isometric and Isotonic Actuation.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Elastomer-granule composites have been used to switch between soft and stiff states by applying negative pressure differentials that cause the membrane to squeeze the internal grains, inducing dilation and jamming. Applications of this phenomenon hav...

Comparison of partial least square, artificial neural network, and support vector regressions for real-time monitoring of CHO cell culture processes using in situ near-infrared spectroscopy.

Biotechnology and bioengineering
The biopharmaceutical industry must guarantee the efficiency and biosafety of biological medicines, which are quite sensitive to cell culture process variability. Real-time monitoring procedures based on vibrational spectroscopy such as near-infrared...

Machine Learning of Bacterial Transcriptomes Reveals Responses Underlying Differential Antibiotic Susceptibility.

mSphere
antibiotic susceptibility testing often fails to accurately predict drug efficacies, in part due to differences in the molecular composition between standardized bacteriologic media and physiological environments within the body. Here, we investiga...

A robust soft sensor to monitor 1,3-propanediol fermentation process by Clostridium butyricum based on artificial neural network.

Biotechnology and bioengineering
With the aggravation of environmental pollution and energy crisis, the sustainable microbial fermentation process of converting glycerol to 1,3-propanediol (1,3-PDO) has become an attractive alternative. However, the difficulty in the online measurem...

Application of automated electron microscopy imaging and machine learning to characterise and quantify nanoparticle dispersion in aqueous media.

Journal of microscopy
For many nanoparticle applications it is important to understand dispersion in liquids. For nanomedicinal and nanotoxicological research this is complicated by the often complex nature of the biological dispersant and ultimately this leads to severe ...

Extraction and optimization of exopolysaccharide from sp. using response surface methodology and artificial neural networks.

Preparative biochemistry & biotechnology
The microbial polysaccharides secreted and produced from various microbes into their extracellular environment is known as exopolysaccharide. These polysaccharides can be secreted from the microbes either in a soluble or insoluble form. sp. is one of...

Optimization of Cultural Conditions for Cultured in Industrial Wastewater.

BioMed research international
The aim of this study was to optimize the cultural conditions for using industrial wastewater as nature culture through response surface methodology. In our present study, we analyzed the total number of living in the fermentation broth using mult...

Evaluation of growth and sporulation of a non-toxigenic strain of Clostridioides difficile (Z31) and its shelf viability.

Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]
The oral administration of non-toxigenic strains of Clostridioides difficile (NTCD) is currently showing promising results for the prevention of Clostridioides difficile infection (CDI) in humans and animals, and is being considered as a possible com...