Pharmacovigilance (PV) is defined by the World Health Organization as the science and activities related to the detection, assessment, understanding and prevention of adverse effects or any other drug-related problem. An essential aspect in PV is to ...
BMC medical informatics and decision making
Sep 30, 2015
BACKGROUND: A plethora of publicly available biomedical resources do currently exist and are constantly increasing at a fast rate. In parallel, specialized repositories are been developed, indexing numerous clinical and biomedical tools. The main dra...
BACKGROUND: Accumulating quantitative outcome parameters may contribute to constructing a healthcare organization in which outcomes of clinical procedures are reproducible and predictable. In imaging studies, measurements are the principal category o...
For the 2014 i2b2/UTHealth de-identification challenge, we introduced a new non-parametric Bayesian hidden Markov model using a Dirichlet process (HMM-DP). The model intends to reduce task-specific feature engineering and to generalize well to new da...
IEEE/ACM transactions on computational biology and bioinformatics
Sep 18, 2015
Although some methods are proposed for automatic ontology generation, none of them address the issue of integrating large-scale heterogeneous biomedical ontologies. We propose a novel approach for integrating various types of ontologies efficiently a...
IEEE/ACM transactions on computational biology and bioinformatics
Sep 14, 2015
In biomedical text mining tasks, distributed word representation has succeeded in capturing semantic regularities, but most of them are shallow-window based models, which are not sufficient for expressing the meaning of words. To represent words usin...
IEEE/ACM transactions on computational biology and bioinformatics
Sep 14, 2015
Recently, feature selection and dimensionality reduction have become fundamental tools for many data mining tasks, especially for processing high-dimensional data such as gene expression microarray data. Gene expression microarray data comprises up t...
International journal of medical informatics
Sep 14, 2015
INTRODUCTION: Unplanned 30-day hospital readmission account for roughly $17 billion in annual Medicare spending. Many factors contribute to unplanned hospital readmissions and multiple models have been developed over the years to predict them. Most r...
Clinical trials are essential for determining whether new interventions are effective. In order to determine the eligibility of patients to enroll into these trials, clinical trial coordinators often perform a manual review of clinical notes in the e...
The second track of the 2014 i2b2 challenge asked participants to automatically identify risk factors for heart disease among diabetic patients using natural language processing techniques for clinical notes. This paper describes a rule-based system ...