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A multilayer multimodal detection and prediction model based on explainable artificial intelligence for Alzheimer's disease.

Scientific reports
Alzheimer's disease (AD) is the most common type of dementia. Its diagnosis and progression detection have been intensively studied. Nevertheless, research studies often have little effect on clinical practice mainly due to the following reasons: (1)...

Deep Learning-Based Acute Ischemic Stroke Lesion Segmentation Method on Multimodal MR Images Using a Few Fully Labeled Subjects.

Computational and mathematical methods in medicine
Acute ischemic stroke (AIS) has been a common threat to human health and may lead to severe outcomes without proper and prompt treatment. To precisely diagnose AIS, it is of paramount importance to quantitatively evaluate the AIS lesions. By adopting...

Machine learning predictive model for severe COVID-19.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases
To develop a modified predictive model for severe COVID-19 in people infected with Sars-Cov-2. We developed the predictive model for severe patients of COVID-19 based on the clinical date from the Tumor Center of Union Hospital affiliated with Tongji...

Machine Learning-Based Prediction of 6-Month Postoperative Karnofsky Performance Status in Patients with Glioblastoma: Capturing the Real-Life Interaction of Multiple Clinical and Oncologic Factors.

World neurosurgery
OBJECTIVE: Ability to thrive after invasive and intensive treatment is an important parameter to assess in patients with glioblastoma multiforme (GBM). Karnofsky Performance Status (KPS) is used to identify those patients suitable for postoperative r...

CardioNet: a manually curated database for artificial intelligence-based research on cardiovascular diseases.

BMC medical informatics and decision making
BACKGROUND: Cardiovascular diseases (CVDs) are difficult to diagnose early and have risk factors that are easy to overlook. Early prediction and personalization of treatment through the use of artificial intelligence (AI) may help clinicians and pati...

An Artificial Neural Networks Model for Early Predicting In-Hospital Mortality in Acute Pancreatitis in MIMIC-III.

BioMed research international
BACKGROUND: Early and accurate evaluation of severity and prognosis in acute pancreatitis (AP), especially at the time of admission is very significant. This study was aimed to develop an artificial neural networks (ANN) model for early prediction of...

Application of deep learning algorithm to detect and visualize vertebral fractures on plain frontal radiographs.

PloS one
BACKGROUND: Identification of vertebral fractures (VFs) is critical for effective secondary fracture prevention owing to their association with the increasing risks of future fractures. Plain abdominal frontal radiographs (PARs) are a common investig...

Wavelet decomposition facilitates training on small datasets for medical image classification by deep learning.

Histochemistry and cell biology
The adoption of low-dose computed tomography (LDCT) as the standard of care for lung cancer screening results in decreased mortality rates in high-risk population while increasing false-positive rate. Convolutional neural networks provide an ideal op...

Towards a Precision Medicine Approach Based on Machine Learning for Tailoring Medical Treatment in Alkaptonuria.

International journal of molecular sciences
ApreciseKUre is a multi-purpose digital platform facilitating data collection, integration and analysis for patients affected by Alkaptonuria (AKU), an ultra-rare autosomal recessive genetic disease. It includes genetic, biochemical, histopathologica...

AI Accelerated Human-in-the-loop Structuring of Radiology Reports.

AMIA ... Annual Symposium proceedings. AMIA Symposium
Rule-based Natural Language Processing (NLP) pipelines depend on robust domain knowledge. Given the long tail of important terminology in radiology reports, it is not uncommon for standard approaches to miss items critical for understanding the image...