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Artificial intelligence supported anemia control system (AISACS) to prevent anemia in maintenance hemodialysis patients.

International journal of medical sciences
Anemia, for which erythropoiesis-stimulating agents (ESAs) and iron supplements (ISs) are used as preventive measures, presents important difficulties for hemodialysis patients. Nevertheless, the number of physicians able to manage such medications a...

Deep Learning for Detection of Elevated Pulmonary Artery Wedge Pressure Using Standard Chest X-Ray.

The Canadian journal of cardiology
BACKGROUND: To accurately diagnose and control heart failure (HF), it is important to carry out a simple assessment of elevated pulmonary arterial wedge pressure (PAWP). The aim of this study was to develop and validate an objective method for detect...

Leveraging innovative technology to generate drug response phenotypes for the advancement of biomarker-driven precision dosing.

Clinical and translational science
Although traditional approaches to biomarker discovery have elucidated key molecular markers that have improved drug selection (precision medicine), the discovery of biomarkers that inform optimal dose selection (precision dosing) continues to be a c...

TAP 1.0: A robust immunoinformatic tool for the prediction of tumor T-cell antigens based on AAindex properties.

Computational biology and chemistry
Immunotherapy is a research area with great potential in drug discovery for cancer treatment. Because of the capacity of tumor antigens to activate the immune response and promote the destruction of tumor cells, they are considered excellent immunoth...

New machine learning and physics-based scoring functions for drug discovery.

Scientific reports
Scoring functions are essential for modern in silico drug discovery. However, the accurate prediction of binding affinity by scoring functions remains a challenging task. The performance of scoring functions is very heterogeneous across different tar...

Aggregation of cohorts for histopathological diagnosis with deep morphological analysis.

Scientific reports
There have been substantial efforts in using deep learning (DL) to diagnose cancer from digital images of pathology slides. Existing algorithms typically operate by training deep neural networks either specialized in specific cohorts or an aggregate ...

Deep learning for the fully automated segmentation of the inner ear on MRI.

Scientific reports
Segmentation of anatomical structures is valuable in a variety of tasks, including 3D visualization, surgical planning, and quantitative image analysis. Manual segmentation is time-consuming and deals with intra and inter-observer variability. To dev...

Algorithmic and human prediction of success in human collaboration from visual features.

Scientific reports
As groups are increasingly taking over individual experts in many tasks, it is ever more important to understand the determinants of group success. In this paper, we study the patterns of group success in Escape The Room, a physical adventure game in...