AIMC Topic: Deep Learning

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Artificial intelligence in gastroenterology: Ethical and diagnostic challenges in clinical practice.

World journal of gastroenterology
This article discusses the manuscript recently published in the , which explores the application of deep learning models in decision-making processes via wireless capsule endoscopy. Integrating artificial intelligence (AI) into gastrointestinal disea...

Predicting early recurrence of hepatocellular carcinoma after thermal ablation based on longitudinal MRI with a deep learning approach.

The oncologist
BACKGROUND: Accurate prediction of early recurrence (ER) is essential to improve the prognosis of patients with hepatocellular carcinoma (HCC) underwent thermal ablation (TA). Therefore, a deep learning model system using longitudinal magnetic resona...

[Scale-invariant feature-enhanced deep learning framework for oral mucosal lesion segmentation].

Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology
To develop PixelSIFT-UNet, a novel semantic segmentation model that integrates deep learning with scale-invariant feature transform (SIFT) algorithm to improve the segmentation accuracy of oral mucosal lesions. This investigation utilized 838 stand...

A deep learning model for characterizing altered gyro-sulcal functional connectivity in abstinent males with methamphetamine use disorder and associated emotional symptoms.

Cerebral cortex (New York, N.Y. : 1991)
Failure to manage emotional withdrawal symptoms can exacerbate relapse to methamphetamine use. Understanding the neuro-mechanisms underlying methamphetamine overuse and the associated emotional withdrawal symptoms is crucial for developing effective ...

Increase Docking Score Screening Power by Simple Fusion With CNNscore.

Journal of computational chemistry
Scoring functions (SFs) of molecular docking is a vital component of structure-based virtual screening (SBVS). Traditional SFs yield their inherent shortage for idealized approximations and simplifications predicting the binding affinity. Complementa...

Deep learning in GPCR drug discovery: benchmarking the path to accurate peptide binding.

Briefings in bioinformatics
Deep learning (DL) methods have drastically advanced structure-based drug discovery by directly predicting protein structures from sequences. Recently, these methods have become increasingly accurate in predicting complexes formed by multiple protein...

PathSynergy: a deep learning model for predicting drug synergy in liver cancer.

Briefings in bioinformatics
Cancer is a major public health problem while liver cancer is the main cause of global cancer-related deaths. The previous study demonstrates that the 5-year survival rate for advanced liver cancer is only 30%. Few of the first-line targeted drugs in...

DEKP: a deep learning model for enzyme kinetic parameter prediction based on pretrained models and graph neural networks.

Briefings in bioinformatics
The prediction of enzyme kinetic parameters is crucial for screening enzymes with high catalytic efficiency and desired characteristics to catalyze natural or non-natural reactions. Data-driven machine learning models have been explored to reduce exp...

Self-awareness of retrosynthesis via chemically inspired contrastive learning for reinforced molecule generation.

Briefings in bioinformatics
The recent progress of deep generative models in modeling complex real-world data distributions has enabled the generation of novel compounds with potential therapeutic applications for various diseases. However, most studies fail to optimize the pro...