To provide an artificial intelligence (AI) method using in vivo confocal microscopy (IVCM) to differentiate ocular surface squamous neoplasia (OSSN) from other lesions and compare the performance of well-known AI-related solutions. A dataset of 2,774...
Accurate prediction of enzyme kinetic parameters is crucial for enzyme exploration and modification. Existing models face the problem of either low accuracy or poor generalization ability due to overfitting. In this work, we first developed unbiased ...
BACKGROUND/ AIMS: The lack of context for anterior segment optical coherence tomography (ASOCT) measurements impedes its clinical utility. We established the normative distribution of anterior chamber depth (ACD), area (ACA) and width (ACW) and lens ...
SAR and QSAR in environmental research
Mar 20, 2025
P38α has been identified as a key target for drug design to treat a wide range of diseases. In this study, multiple independent Gaussian accelerated molecular dynamics (GaMD) simulations, deep learning (DL), and the molecular mechanics generalized Bo...
Deep Neural Networks (DNN) have achieved state-of-the-art performance in medical image classification and are increasingly being used for disease diagnosis. However, these models are quite complex and that necessitates the need to reduce the model co...
Under the increasing pressure of global climate change, water conservation (WC) in semi-arid regions is experiencing unprecedented levels of stress. WC involves complex, nonlinear interactions among ecosystem components like vegetation, soil structur...
Extreme heat waves are causing widespread concern for comprehensive studies on their ecological and societal implications. With the ongoing rise in global temperatures, precise forecasting of heatwaves becomes increasingly crucial for proactive plann...
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Mar 19, 2025
BACKGROUND: In the HECKTOR 2022 challenge set [1], several state-of-the-art (SOTA, achieving best performance) deep learning models were introduced for predicting recurrence-free period (RFP) in head and neck cancer patients using PET and CT images.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association
Mar 19, 2025
Acrylamide (AA), a food hazard generated during thermal processing, poses significant safety risks due to its toxicity. Conventional methods for AA toxicology are time-consuming and inadequate for analyzing cellular morphology. This study developed a...
Journal of applied clinical medical physics
Mar 19, 2025
PURPOSE: Balancing quality and efficiency has been a challenge for online adaptive therapy. Most systems start the online re-optimization with the original planning goals. While some systems allow planners to modify the planning goals, achieving a hi...
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