AIMC Topic: Deep Learning

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FUN-PROSE: A deep learning approach to predict condition-specific gene expression in fungi.

PLoS computational biology
mRNA levels of all genes in a genome is a critical piece of information defining the overall state of the cell in a given environmental condition. Being able to reconstruct such condition-specific expression in fungal genomes is particularly importan...

A deep learning analysis of stroke onset time prediction and comparison to DWI-FLAIR mismatch.

NeuroImage. Clinical
INTRODUCTION: When time since stroke onset is unknown, DWI-FLAIR mismatch rating is an established technique for patient stratification. A visible DWI lesion without corresponding parenchymal hyperintensity on FLAIR suggests time since onset of under...

MRI-based automated multitask deep learning system to evaluate supraspinatus tendon injuries.

European radiology
OBJECTIVE: To establish an automated, multitask, MRI-based deep learning system for the detailed evaluation of supraspinatus tendon (SST) injuries.

Deep learning generated lower extremity radiographic measurements are adequate for quick assessment of knee angular alignment and leg length determination.

Skeletal radiology
PURPOSE: Angular and longitudinal deformities of leg alignment create excessive stresses across joints, leading to pain and impaired function. Multiple measurements are used to assess these deformities on anteroposterior (AP) full-length radiographs....

Assessment of deep learning-based auto-contouring on interobserver consistency in target volume and organs-at-risk delineation for breast cancer: Implications for RTQA program in a multi-institutional study.

Breast (Edinburgh, Scotland)
PURPOSE: To quantify interobserver variation (IOV) in target volume and organs-at-risk (OAR) contouring across 31 institutions in breast cancer cases and to explore the clinical utility of deep learning (DL)-based auto-contouring in reducing potentia...

Predicting stroke outcome: A case for multimodal deep learning methods with tabular and CT Perfusion data.

Artificial intelligence in medicine
MOTIVATION: Acute ischemic stroke is one of the leading causes of morbidity and disability worldwide, often followed by a long rehabilitation period. To improve and personalize stroke rehabilitation, it is essential to provide a reliable prognosis to...

Deep learning based histological classification of adnex tumors.

European journal of cancer (Oxford, England : 1990)
BACKGROUND: Cutaneous adnexal tumors are a diverse group of tumors arising from structures of the hair appendages. Although often benign, malignant entities occur which can metastasize and lead to patients´ death. Correct diagnosis is critical to ens...

Utilizing deep learning techniques to improve image quality and noise reduction in preclinical low-dose PET images in the sinogram domain.

Medical physics
BACKGROUND: Low-dose positron emission tomography (LD-PET) imaging is commonly employed in preclinical research to minimize radiation exposure to animal subjects. However, LD-PET images often exhibit poor quality and high noise levels due to the low ...

Predicting glaucoma progression using deep learning framework guided by generative algorithm.

Scientific reports
Glaucoma is a slowly progressing optic neuropathy that may eventually lead to blindness. To help patients receive customized treatment, predicting how quickly the disease will progress is important. Structural assessment using optical coherence tomog...

Deep learning of human polyadenylation sites at nucleotide resolution reveals molecular determinants of site usage and relevance in disease.

Nature communications
The genomic distribution of cleavage and polyadenylation (polyA) sites should be co-evolutionally optimized with the local gene structure. Otherwise, spurious polyadenylation can cause premature transcription termination and generate aberrant protein...