Major depressive disorder (MDD) is associated with substantial morbidity and mortality, yet its diagnosis and treatment rates remain low due to its diverse and often overlapping clinical manifestations. In this context, electroencephalography (EEG) h...
Depression treatment responses vary widely among individuals. Identifying objective biomarkers with predictive accuracy for therapeutic outcomes can enhance treatment efficiency and avoid ineffective therapies. This study investigates whether functio...
Major Depressive Disorder (MDD) is a prevalent mental health condition that often begins in adolescence, with significant long-term implications. Indicated prevention programs targeting adolescents with mild symptoms have shown efficacy, yet the meth...
Late-onset depression (LOD) refers to depression that newly appears in elderly individuals without prior depression episodes. Predicting future depression is crucial for mitigating the risk of major depression in prospective patients. This study aims...
The diagnosis and analysis of major depressive disorder (MDD) faces some intractable challenges such as dataset limitations and clinical variability. Resting-state functional magnetic resonance imaging (Rs-fMRI) can reflect the fluctuation data of br...
BACKGROUND: Mobile devices for remote monitoring are inevitable tools to support treatment and patient care, especially in recurrent diseases such as major depressive disorder. The aim of this study was to learn if machine learning (ML) models based ...
Journal of pharmacokinetics and pharmacodynamics
Dec 10, 2024
In randomized, placebo controlled clinical trials (RCT) in major depressive disorders (MDD), treatment response (TR) is estimated by the change from baseline at study-end (EOS) of the scores of clinical scales used for assessing disease severity. Tre...
Major Depressive Disorder (MDD) is a common mental disorder characterized by cognitive impairment, and its pathophysiology remains to be explored. In this study, we aimed to explore the efficacy of brain network topological properties (TPs) in identi...
BACKGROUND: The genetic determinants of peripartum depression (PPD) are not fully understood. Using a multi-polygenic score approach, we characterized the relationship between genome-wide information and the history of PPD in patients with mood disor...
INTRODUCTION: Major depressive disorder (MDD) is a common, relapse-prone psychiatric disorder with unknown pathogenesis. Previous studies on resting-state functional magnetic resonance imaging of MDD have mostly focused on the spontaneous activity of...
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