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Diabetes Mellitus, Type 1

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Predictors of glycaemic improvement in children and young adults with type 1 diabetes and very elevated HbA1c using the MiniMed 780G system.

Diabetes, obesity & metabolism
AIMS: This study aimed to identify key factors with the greatest influence on glycaemic outcomes in young individuals with type 1 diabetes (T1D) and very elevated glycaemia after 3 months of automated insulin delivery (AID).

Parental perspectives following the implementation of advanced hybrid closed-loop therapy in children and adolescents with type 1 diabetes and elevated glycaemia.

Diabetic medicine : a journal of the British Diabetic Association
AIMS: To identify from a parental perspective facilitators and barriers of effective implementation of advanced hybrid closed-loop (AHCL) therapy in children and adolescents with type 1 diabetes (T1D) with elevated glycaemia.

Predicting Antidiabetic Peptide Activity: A Machine Learning Perspective on Type 1 and Type 2 Diabetes.

International journal of molecular sciences
Diabetes mellitus (DM) presents a critical global health challenge, characterized by persistent hyperglycemia and associated with substantial economic and health-related burdens. This study employs advanced machine-learning techniques to improve the ...

Hybrid CNN-GRU Model for Real-Time Blood Glucose Forecasting: Enhancing IoT-Based Diabetes Management with AI.

Sensors (Basel, Switzerland)
For people with diabetes, controlling blood glucose level (BGL) is a significant issue since the disease affects how the body metabolizes food, which makes careful insulin regulation necessary. Patients have to manually check their blood sugar levels...

A prior-knowledge-guided dynamic attention mechanism to predict nocturnal hypoglycemic events in type 1 diabetes.

BMC medical informatics and decision making
Nocturnal hypoglycemia is a critical problem faced by diabetic patients. Failure to intervene in time can be dangerous for patients. The existing early warning methods struggle to extract crucial information comprehensively from complex multi-source ...

Leveraging artificial intelligence and machine learning to accelerate discovery of disease-modifying therapies in type 1 diabetes.

Diabetologia
Progress in developing therapies for the maintenance of endogenous insulin secretion in, or the prevention of, type 1 diabetes has been hindered by limited animal models, the length and cost of clinical trials, difficulties in identifying individuals...

A safe-enhanced fully closed-loop artificial pancreas controller based on deep reinforcement learning.

PloS one
Patients with type 1 diabetes and their physicians have long desired a fully closed-loop artificial pancreas (AP) system that can alleviate the burden of blood glucose regulation. Although deep reinforcement learning (DRL) methods theoretically enabl...

Predicting and Ranking Diabetic Ketoacidosis Risk Among Youth with Type 1 Diabetes with a Clinic-to-Clinic Transferrable Machine Learning Model.

Diabetes technology & therapeutics
To use electronic health record (EHR) data to develop a scalable and transferrable model to predict 6-month risk for diabetic ketoacidosis (DKA)-related hospitalization or emergency care in youth with type 1 diabetes (T1D). To achieve a sharable pr...

Hybrid Control Policy for Artificial Pancreas via Ensemble Deep Reinforcement Learning.

IEEE transactions on bio-medical engineering
OBJECTIVE: The artificial pancreas (AP) shows promise for closed-loop glucose control in type 1 diabetes mellitus (T1DM). However, designing effective control policies for the AP remains challenging due to complex physiological processes, delayed ins...

Personalized Blood Glucose Forecasting From Limited CGM Data Using Incrementally Retrained LSTM.

IEEE transactions on bio-medical engineering
For people with Type 1 diabetes (T1D), accurate blood glucose (BG) forecasting is crucial for the effective delivery of insulin by Artificial Pancreas (AP) systems. Deep learning frameworks like Long Short-Term-Memory (LSTM) have been widely used to ...