AIMC Topic: Diabetes Mellitus, Type 1

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Intervention through an intelligent technological platform for socio-emotional development and health promotion in adolescents with Type 1 Diabetes Mellitus (emoTICare): A study protocol for randomized controlled trial.

PloS one
BACKGROUND: During adolescence, individuals face various challenges that require adequate psychosocial and emotional adjustment. Additionally, the presence of a chronic illness during this stage, such as Type 1 Diabetes Mellitus (T1DM), introduces ad...

Insulin resistance in type 1 diabetes is a key modulator of platelet hyperreactivity.

Diabetologia
AIMS/HYPOTHESIS: Individuals with type 1 diabetes are at increased cardiovascular risk, particularly in the presence of insulin resistance. A prothrombotic environment is believed to contribute to this risk but thrombotic pathways in type 1 diabetes ...

Modeling the number of new cases of childhood type 1 diabetes using Poisson regression and machine learning methods; a case study in Saudi Arabia.

PloS one
Diabetes mellitus stands out as one of the most prevalent chronic conditions affecting pediatric populations. The escalating incidence of childhood type 1 diabetes (T1D) globally is a matter of increasing concern. Developing an effective model that l...

Personalized glucose forecasting for people with type 1 diabetes using large language models.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Type 1 Diabetes (T1D) is an autoimmune disease that requires exogenous insulin via Multiple Daily Injections (MDIs) or subcutaneous pumps to maintain targeted glucose levels. Despite the advances in Continuous Glucose Monito...

Personalized Blood Glucose Forecasting From Limited CGM Data Using Incrementally Retrained LSTM.

IEEE transactions on bio-medical engineering
For people with Type 1 diabetes (T1D), accurate blood glucose (BG) forecasting is crucial for the effective delivery of insulin by Artificial Pancreas (AP) systems. Deep learning frameworks like Long Short-Term-Memory (LSTM) have been widely used to ...

Identification and validation of endoplasmic reticulum stress-related diagnostic biomarkers for type 1 diabetic cardiomyopathy based on bioinformatics and machine learning.

Frontiers in endocrinology
BACKGROUND: Diabetic cardiomyopathy (DC) is a serious complication in patients with type 1 diabetes mellitus and has become a growing public health problem worldwide. There is evidence that endoplasmic reticulum stress (ERS) is involved in the pathog...

Disease diagnostics using machine learning of B cell and T cell receptor sequences.

Science (New York, N.Y.)
Clinical diagnosis typically incorporates physical examination, patient history, various laboratory tests, and imaging studies but makes limited use of the human immune system's own record of antigen exposures encoded by receptors on B cells and T ce...

Deep learning-based prediction of autoimmune diseases.

Scientific reports
Autoimmune Diseases are a complex group of diseases caused by the immune system mistakenly attacking body tissues. Their etiology involves multiple factors such as genetics, environmental factors, and abnormalities in immune cells, making prediction ...

GARNN: An interpretable graph attentive recurrent neural network for predicting blood glucose levels via multivariate time series.

Neural networks : the official journal of the International Neural Network Society
Accurate prediction of future blood glucose (BG) levels can effectively improve BG management for people living with type 1 or 2 diabetes, thereby reducing complications and improving quality of life. The state of the art of BG prediction has been ac...

Optimizing hypoglycaemia prediction in type 1 diabetes with Ensemble Machine Learning modeling.

BMC medical informatics and decision making
BACKGROUND: Type 1 diabetes (T1D) is a chronic endocrine disorder characterized by high blood glucose levels, impacting millions of people globally. Its management requires intensive insulin therapy, frequent blood glucose monitoring, and lifestyle a...