BACKGROUND: Diabetic cardiomyopathy (DC) is a serious complication in patients with type 1 diabetes mellitus and has become a growing public health problem worldwide. There is evidence that endoplasmic reticulum stress (ERS) is involved in the pathog...
Clinical diagnosis typically incorporates physical examination, patient history, various laboratory tests, and imaging studies but makes limited use of the human immune system's own record of antigen exposures encoded by receptors on B cells and T ce...
Autoimmune Diseases are a complex group of diseases caused by the immune system mistakenly attacking body tissues. Their etiology involves multiple factors such as genetics, environmental factors, and abnormalities in immune cells, making prediction ...
Neural networks : the official journal of the International Neural Network Society
Feb 5, 2025
Accurate prediction of future blood glucose (BG) levels can effectively improve BG management for people living with type 1 or 2 diabetes, thereby reducing complications and improving quality of life. The state of the art of BG prediction has been ac...
BMC medical informatics and decision making
Jan 31, 2025
BACKGROUND: Type 1 diabetes (T1D) is a chronic endocrine disorder characterized by high blood glucose levels, impacting millions of people globally. Its management requires intensive insulin therapy, frequent blood glucose monitoring, and lifestyle a...
Patients with type 1 diabetes and their physicians have long desired a fully closed-loop artificial pancreas (AP) system that can alleviate the burden of blood glucose regulation. Although deep reinforcement learning (DRL) methods theoretically enabl...
AIMS: This study aimed to identify key factors with the greatest influence on glycaemic outcomes in young individuals with type 1 diabetes (T1D) and very elevated glycaemia after 3 months of automated insulin delivery (AID).
IEEE transactions on bio-medical engineering
Jan 15, 2025
OBJECTIVE: The artificial pancreas (AP) shows promise for closed-loop glucose control in type 1 diabetes mellitus (T1DM). However, designing effective control policies for the AP remains challenging due to complex physiological processes, delayed ins...
Nutrition, metabolism, and cardiovascular diseases : NMCD
Jan 9, 2025
BACKGROUND AND AIMS: Type 1 diabetes and diabetic ketoacidosis (DKA) have a significant impact on individuals and society across a wide spectrum. Our objective was to utilize machine learning techniques to predict DKA and HbA1c>7 %.
To use electronic health record (EHR) data to develop a scalable and transferrable model to predict 6-month risk for diabetic ketoacidosis (DKA)-related hospitalization or emergency care in youth with type 1 diabetes (T1D). To achieve a sharable pr...
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