AIMC Topic: Diagnostic Tests, Routine

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Whole-brain death and integration: realigning the ontological concept with clinical diagnostic tests.

Theoretical medicine and bioethics
For decades, physicians, philosophers, theologians, lawyers, and the public considered brain death a settled issue. However, a series of recent cases in which individuals were declared brain dead yet physiologically maintained for prolonged periods o...

Supervised machine learning for the prediction of infection on admission to hospital: a prospective observational cohort study.

The Journal of antimicrobial chemotherapy
BACKGROUND: Infection diagnosis can be challenging, relying on clinical judgement and non-specific markers of infection. We evaluated a supervised machine learning (SML) algorithm for diagnosing bacterial infection using routinely available blood par...

Precision immunoprofiling to reveal diagnostic signatures for latent tuberculosis infection and reactivation risk stratification.

Integrative biology : quantitative biosciences from nano to macro
Latent tuberculosis infection (LTBI) is estimated in nearly one quarter of the world's population, and of those immunocompetent and infected ~10% will proceed to active tuberculosis (TB). Current diagnostics cannot definitively identify LTBI and prov...

NT-proBNP test with improved accuracy for the diagnosis of chronic heart failure.

Medicine
The circulating concentration of N-terminal pro-brain natriuretic peptide (NT-proBNP) has been shown to be a diagnostic tool for the detection of heart failure. Several factors influence NT-proBNP levels including age, sex, and body mass index (BMI)....