AIMC Topic: Dogs

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Sperm Tail Defects and Abnormal Testicular Blood Flow in a Beagle Dog: A Case Report.

Topics in companion animal medicine
A 5-year-old male Beagle dog produced ejaculates with a high percentage of spermatozoa with abnormal morphology, especially sperm tail defects. Although libido and semen volume were normal, ejaculates showed asthenospermia, oligozoospermia, and terat...

Multi-resolution convolutional neural networks for fully automated segmentation of acutely injured lungs in multiple species.

Medical image analysis
Segmentation of lungs with acute respiratory distress syndrome (ARDS) is a challenging task due to diffuse opacification in dependent regions which results in little to no contrast at the lung boundary. For segmentation of severely injured lungs, loc...

Deep learning-based MR-to-CT synthesis: The influence of varying gradient echo-based MR images as input channels.

Magnetic resonance in medicine
PURPOSE: To study the influence of gradient echo-based contrasts as input channels to a 3D patch-based neural network trained for synthetic CT (sCT) generation in canine and human populations.

CNN-based diagnosis models for canine ulcerative keratitis.

Scientific reports
The purpose of this methodological study was to develop a convolutional neural network (CNN), which is a recently developed deep-learning-based image recognition method, to determine corneal ulcer severity in dogs. The CNN model was trained with imag...

Making Sense of Pharmacovigilance and Drug Adverse Event Reporting: Comparative Similarity Association Analysis Using AI Machine Learning Algorithms in Dogs and Cats.

Topics in companion animal medicine
Drug-associated adverse events cause approximately 30 billion dollars a year of added health care expense, along with negative health outcomes including patient death. This constitutes a major public health concern. The US Food and Drug Administratio...

Using machine learning to understand neuromorphological change and image-based biomarker identification in Cavalier King Charles Spaniels with Chiari-like malformation-associated pain and syringomyelia.

Journal of veterinary internal medicine
BACKGROUND: Chiari-like malformation (CM) is a complex malformation of the skull and cranial cervical vertebrae that potentially results in pain and secondary syringomyelia (SM). Chiari-like malformation-associated pain (CM-P) can be challenging to d...

Machine learning algorithm as a diagnostic tool for hypoadrenocorticism in dogs.

Domestic animal endocrinology
Canine hypoadrenocorticism (CHA) is a life-threatening condition that affects approximately 3 of 1,000 dogs. It has a wide array of clinical signs and is known to mimic other disease processes, including kidney and gastrointestinal diseases, creating...

Bio-inspired robotic dog paddling: kinematic and hydro-dynamic analysis.

Bioinspiration & biomimetics
Research on quadrupedal robots inspired by canids or felids have been widely reported and demonstrated. However, none of these legged robots can deal with difficult environments that include water, such as small lakes, streams, rain, mud, flooded ter...

Deep learning enables rapid identification of potent DDR1 kinase inhibitors.

Nature biotechnology
We have developed a deep generative model, generative tensorial reinforcement learning (GENTRL), for de novo small-molecule design. GENTRL optimizes synthetic feasibility, novelty, and biological activity. We used GENTRL to discover potent inhibitors...