AIMC Topic: Drug Delivery Systems
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Use of Model Predictive Control and Artificial Neural Networks to Optimize the Ultrasonic Release of a Model Drug From Liposomes.
IEEE transactions on nanobioscience
Jan 30, 2017
The use of echogenic liposomes to deliver chemotherapeutic agents for cancer treatment has gained wide recognition in the last 20 years. Cancerous cells can develop multiple drug resistance (MDR), in part, due to the drop in concentration of chemothe...
Artificial intelligence in medicine.
Metabolism: clinical and experimental
Jan 11, 2017
Artificial Intelligence (AI) is a general term that implies the use of a computer to model intelligent behavior with minimal human intervention. AI is generally accepted as having started with the invention of robots. The term derives from the Czech ...
A renaissance of neural networks in drug discovery.
Expert opinion on drug discovery
Jul 4, 2016
INTRODUCTION: Neural networks are becoming a very popular method for solving machine learning and artificial intelligence problems. The variety of neural network types and their application to drug discovery requires expert knowledge to choose the mo...
Brain-inspired cheminformatics of drug-target brain interactome, synthesis, and assay of TVP1022 derivatives.
Neuropharmacology
Dec 23, 2015
The use of Cheminformatics tools is gaining importance in the field of translational research from Medicinal Chemistry to Neuropharmacology. In particular, we need it for the analysis of chemical information on large datasets of bioactive compounds. ...
Formulation of Granules for Site-Specific Delivery of an Antimicrobial Essential Oil to the Animal Intestinal Tract.
Journal of pharmaceutical sciences
Dec 23, 2015
Owing to proliferation of antibiotic-resistant bacteria, the use of antibiotics for livestock growth promotion is banned in many countries and alternatives to in-feed antibiotics are needed. Cinnamon essential oil exhibits strong in vitro antibacteri...
RenalGuard system in high-risk patients for contrast-induced acute kidney injury.
American heart journal
Dec 17, 2015
BACKGROUND: High urine flow rate (UFR) has been suggested as a target for effective prevention of contrast-induced acute kidney injury (CI-AKI). The RenalGuard therapy (saline infusion plus furosemide controlled by the RenalGuard system) facilitates ...
Angiography
Risk Factors
Urodynamics
Aged
Furosemide
Humans
Sodium Chloride
Contrast Media
Glomerular Filtration Rate
Drug Delivery Systems
Prospective Studies
Diuretics
Equipment Design
Male
Drug Combinations
Isotonic Solutions
Coronary Artery Disease
Acute Kidney Injury
Follow-Up Studies
Creatinine
Female
Predicting Drug-Target Interactions via Within-Score and Between-Score.
BioMed research international
Oct 12, 2015
Network inference and local classification models have been shown to be useful in predicting newly potential drug-target interactions (DTIs) for assisting in drug discovery or drug repositioning. The idea is to represent drugs, targets, and their int...
Hydrophilic Ionic Liquids as Ingredients of Gel-Based Dermal Formulations.
AAPS PharmSciTech
Oct 1, 2015
Ionic liquids (ILs) have several properties that offer many advantages in dermal drug delivery systems. Depending on the chemical structure, ILs can be used for protection against microorganisms, to enhance skin penetration, and as a solvent. In the ...
Towards soft robotic devices for site-specific drug delivery.
Expert review of medical devices
Sep 28, 2015
Considerable research efforts have recently been dedicated to the establishment of various drug delivery systems (DDS) that are mechanical/physical, chemical and biological/molecular DDS. In this paper, we report on the recent advances in site-specif...
Magnetic nanoparticles and nanocomposites for remote controlled therapies.
Journal of controlled release : official journal of the Controlled Release Society
Sep 25, 2015
This review highlights the state-of-the-art in the application of magnetic nanoparticles (MNPs) and their composites for remote controlled therapies. Novel macro- to nano-scale systems that utilize remote controlled drug release due to actuation of M...
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