AIMC Topic: Early Diagnosis

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Dynamically weighted graph neural network for detection of early mild cognitive impairment.

PloS one
Alzheimer's disease (AD) is a prevalent neurodegenerative disease that primarily affects the elderly population. The early detection of mild cognitive impairment (MCI) holds significant clinical importance for prompt intervention and treatment of AD....

A systematic review: Brain age gap as a promising early diagnostic biomarker for Alzheimer's disease.

Journal of the neurological sciences
Alzheimer's disease (AD) is a progressive neurodegenerative disorder for which there is currently no cure, and its incidence is on the rise. Early detection is essential for timely intervention and slowing the progression of the disease. While the br...

Early detection of occupational stress: Enhancing workplace safety with machine learning and large language models.

PloS one
Occupational stress is a major concern for employers and organizations as it compromises decision-making and overall safety of workers. Studies indicate that work-stress contributes to severe mental strain, increased accident rates, and in extreme ca...

Integrated plasma and vegetation proteomic characterization of infective endocarditis for early diagnosis and treatment.

Nature communications
Infective endocarditis, a life-threatening condition, poses challenges for early diagnosis and personalized treatment due to insufficient biomarkers and limited understanding of its pathophysiology. Here, we performed proteomic profiling of plasma an...

Diagnosis of early idiopathic pulmonary fibrosis: current status and future perspective.

Respiratory research
The standard approach to diagnosing idiopathic pulmonary fibrosis (IPF) includes identifying the usual interstitial pneumonia (UIP) pattern via high resolution computed tomography (HRCT) or lung biopsy and excluding known causes of interstitial lung ...

Proteomic-based biomarker discovery reveals panels of diagnostic biomarkers for early identification of heart failure subtypes.

Journal of translational medicine
BACKGROUND: Limited access to echocardiography can delay the diagnosis of suspected heart failure (HF), which in turn postpones the initiation of optimal guideline-directed medical therapy. Although natriuretic peptides like B-type natriuretic peptid...

Early detection of Alzheimer's disease progression stages using hybrid of CNN and transformer encoder models.

Scientific reports
Alzheimer's disease (AD) is a neurodegenerative disorder that affects memory and cognitive functions. Manual diagnosis is prone to human error, often leading to misdiagnosis or delayed detection. MRI techniques help visualize the fine tissues of the ...

Advancement in early diagnosis of polycystic ovary syndrome: biomarker-driven innovative diagnostic sensor.

Mikrochimica acta
Polycystic ovary syndrome (PCOS) is a heterogeneous multifactorial endocrine disorder that affects one in five women around the globe. The pathology suggests a strong polygenic and epigenetic correlation, along with hormonal and metabolic dysfunction...

A hybrid deep learning framework for early detection of diabetic retinopathy using retinal fundus images.

Scientific reports
Recent advancements in deep learning have significantly impacted medical image processing domain, enabling sophisticated and accurate diagnostic tools. This paper presents a novel hybrid deep learning framework that combines convolutional neural netw...

Development and external validation of a machine learning model for cardiac valve calcification early screening in dialysis patients: a multicenter study.

Renal failure
BACKGROUND: Cardiac valve calcification (CVC) is common in dialysis patients and associated with increased cardiovascular risk. However, early screening has been limited by cost concerns. This study aimed to develop and validate a machine learning mo...