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Electronic Health Records

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Comparative ranking of marginal confounding impact of natural language processing-derived versus structured features in pharmacoepidemiology.

Computers in biology and medicine
OBJECTIVE: To explore the ability of natural language processing (NLP) methods to identify confounder information beyond what can be identified using claims codes alone for pharmacoepidemiology.

A series of natural language processing for predicting tumor response evaluation and survival curve from electronic health records.

BMC medical informatics and decision making
BACKGROUND: The clinical information housed within unstructured electronic health records (EHRs) has the potential to promote cancer research. The National Cancer Center Hospital (NCCH) is widely recognized as a leading institution for the treatment ...

De-identification of clinical notes with pseudo-labeling using regular expression rules and pre-trained BERT.

BMC medical informatics and decision making
BACKGROUND: De-identification of clinical notes is essential to utilize the rich information in unstructured text data in medical research. However, only limited work has been done in removing personal information from clinical notes in Korea.

An effective multi-step feature selection framework for clinical outcome prediction using electronic medical records.

BMC medical informatics and decision making
BACKGROUND: Identifying key variables is essential for developing clinical outcome prediction models based on high-dimensional electronic medical records (EMR). However, despite the abundance of feature selection (FS) methods available, challenges re...

Adaptable graph neural networks design to support generalizability for clinical event prediction.

Journal of biomedical informatics
OBJECTIVE: While many machine learning and deep learning-based models for clinical event prediction leverage various data elements from electronic healthcare records such as patient demographics and billing codes, such models face severe challenges w...

Exploring Potential Medications for Alzheimer's Disease with Psychosis by Integrating Drug Target Information into Deep Learning Models: A Data-Driven Approach.

International journal of molecular sciences
Approximately 50% of Alzheimer's disease (AD) patients develop psychotic symptoms, leading to a subtype known as psychosis in AD (AD + P), which is associated with accelerated cognitive decline compared to AD without psychosis. Currently, no FDA-appr...

Prediction of 90 day mortality in elderly patients with acute HF from e-health records using artificial intelligence.

ESC heart failure
AIMS: Mortality risk after hospitalization for heart failure (HF) is high, especially in the first 90 days. This study aimed to construct a model automatically predicting 90 day post-discharge mortality using electronic health record (EHR) data 48 h ...

Reliability-enhanced data cleaning in biomedical machine learning using inductive conformal prediction.

PLoS computational biology
Accurately labeling large datasets is important for biomedical machine learning yet challenging while modern data augmentation methods may generate noise in the training data, which may deteriorate machine learning model performance. Existing approac...

Empowering large language models for automated clinical assessment with generation-augmented retrieval and hierarchical chain-of-thought.

Artificial intelligence in medicine
BACKGROUND: Understanding and extracting valuable information from electronic health records (EHRs) is important for improving healthcare delivery and health outcomes. Large language models (LLMs) have demonstrated significant proficiency in natural ...

Natural language processing techniques applied to the electronic health record in clinical research and practice - an introduction to methodologies.

Computers in biology and medicine
Natural Language Processing (NLP) has the potential to revolutionise clinical research utilising Electronic Health Records (EHR) through the automated analysis of unstructured free text. Despite this potential, relatively few applications have entere...