Early detection of pancreatic cancer (PC) remains challenging largely due to the low population incidence and few known risk factors. However, screening in at-risk populations and detection of early cancer has the potential to significantly alter sur...
International journal of medical informatics
Apr 4, 2025
OBJECTIVE: Determine the efficacy of commonly used approaches to handling missing and/or imbalanced Electronic Health Record (EHR) data on the performance of predictive models targeting risk of admission, intensive care unit (ICU) use, or prolonged l...
Artificial intelligence makes strides in specialized diagnostics but faces challenges in complex clinical scenarios, such as rare disease diagnosis and emergency condition identification. To address these limitations, we develop Meta General Practiti...
BACKGROUND: Depression treatment guidelines emphasize measurement-based care using patient-reported outcome measures, yet their impact on narrative documentation quality remains underexplored.
Adults with opioid use disorder (OUD) are at increased risk for opioid-related complications and repeated hospital admissions. Routine screening for patients at risk for an OUD to prevent complications is not standard practice in many hospitals, lead...
BACKGROUND: The use of patient-reported outcome measures (PROMs) is an expected component of high-quality, measurement-based chiropractic care. The largest health care system offering integrated chiropractic care is the Veterans Health Administration...
Philosophical transactions. Series A, Mathematical, physical, and engineering sciences
Apr 2, 2025
Estimation of cardiovascular model parameters from electronic health records (EHRs) poses a significant challenge primarily due to lack of identifiability. Structural non-identifiability arises when a manifold in the space of parameters is mapped to ...
OBJECTIVE: Identification of clinically meaningful subphenotypes of disease progression can enhance the understanding of disease heterogeneity and underlying pathophysiology. In this study, we propose a machine learning framework to identify subpheno...
BMC medical informatics and decision making
Mar 31, 2025
BACKGROUND: The integration of big data and artificial intelligence (AI) in healthcare, particularly through the analysis of electronic health records (EHR), presents significant opportunities for improving diagnostic accuracy and patient outcomes. H...
BACKGROUND: Alzheimer disease and related dementias (ADRD) exhibit prominent heterogeneity. Identifying clinically meaningful ADRD subtypes is essential for tailoring treatments to specific patient phenotypes.
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