BACKGROUND: Prediction models have demonstrated a range of applications across medicine, including using electronic health record (EHR) data to identify hospital readmission and mortality risk. Large language models (LLMs) can transform unstructured ...
OBJECTIVES: To develop a machine learning-based prediction model using clinical data from the first 24 h of ICU admission to enable rapid screening and early intervention for sepsis patients.
INTRODUCTION: Patients with activated PI3Kδ syndrome (APDS) may elude diagnoses for nearly a decade. Methods to hasten the identification of these patients, and other patients with inborn errors of immunity (IEIs), are needed. We sought to demonstrat...
OBJECTIVES: We aimed to evaluate the performance of multiple large language models (LLMs) in data extraction from unstructured and semi-structured electronic health records.
Digital health technologies have a crucial role in streamlining the use of genomics and facilitating access to genomic health care. There are efforts to integrate genomic information into electronic health records and use artificial intelligence to a...
International journal of medical informatics
Jan 17, 2025
BACKGROUND: ANCA-associated vasculitis (AAV) is a rare but serious disease. Traditional case-identification methods using claims data can be time-intensive and may miss important subgroups. We hypothesized that a deep learning model analyzing electro...
The development of new therapeutic strategies such as immune checkpoint inhibitors (ICIs) and targeted therapies has increased the complexity of the treatment landscape for solid tumors. At the current rate of annual FDA approvals, the potential trea...
BMC medical informatics and decision making
Jan 13, 2025
BACKGROUND: Anhedonia and suicidal ideation are symptoms of major depressive disorder (MDD) that are not regularly captured in structured scales but may be captured in unstructured clinical notes. Natural language processing (NLP) techniques may be u...
BACKGROUND: Natural language processing (NLP) and machine learning (ML) techniques may help harness unstructured free-text electronic health record (EHR) data to detect adverse drug events (ADEs) and thus improve pharmacovigilance. However, evidence ...
The international journal of cardiovascular imaging
Jan 9, 2025
Amid an aging global population, heart failure has become a leading cause of hospitalization among older people. Its high prevalence and mortality rates underscore the importance of accurate mortality prediction for swift disease progression assessme...
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