AI Medical Compendium Topic

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Embryonic Development

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Influence of post-insemination nutrition on embryonic development in beef heifers.

Theriogenology
Previous studies have demonstrated that a decrease in nutrition immediately following AI reduces pregnancy success in beef heifers. The objective of this experiment was to determine if nutrient restriction following AI impacted early embryonic develo...

The potential of AOP networks for reproductive and developmental toxicity assay development.

Reproductive toxicology (Elmsford, N.Y.)
Historically, the prediction of reproductive and developmental toxicity has largely relied on the use of animals. The adverse outcome pathway (AOP) framework forms a basis for the development of new non-animal test methods. It also provides biologica...

McEnhancer: predicting gene expression via semi-supervised assignment of enhancers to target genes.

Genome biology
Transcriptional enhancers regulate spatio-temporal gene expression. While genomic assays can identify putative enhancers en masse, assigning target genes is a complex challenge. We devised a machine learning approach, McEnhancer, which links target g...