AIMC Topic: Environmental Exposure

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Exposure experiments and machine learning revealed that personal care products can significantly increase transdermal exposure of SVOCs from the environment.

Journal of hazardous materials
We investigated the impacts of personal care products (PCPs) on dermal exposure to semi-volatile organic compounds (SVOCs), including phthalates, organophosphate esters, polycyclic aromatic hydrocarbons (PAHs), ultraviolet filters, and p-phenylenedia...

Assessing chemical exposure risk in breastfeeding infants: An explainable machine learning model for human milk transfer prediction.

Ecotoxicology and environmental safety
Breast milk is essential for infant health, but the transfer of xenobiotic chemicals poses significant risks. Ethical challenges in clinical trials necessitate the use of in vitro predictive models to assess chemical exposure risks in breastfeeding i...

Prediction of p-phenylenediamine antioxidant concentrations in human urine using machine learning models.

Journal of hazardous materials
p-phenylenediamine antioxidants (PPDs) are extensively used in rubber manufacturing for their potent antioxidative properties, but PPDs and 2-anilino-5-[(4-methylpentan-2yl)amino]cyclohexa-2,5-diene-1,4-dione (6PPDQ) pose potential environmental and ...

Blood metal levels predict digestive tract cancer risk using machine learning in a U.S. cohort.

Scientific reports
BACKGROUND: Environmental metal exposure has been implicated in the development of digestive tract cancers, although the specific associations remain poorly defined. This study aimed to investigate the relationship between blood metal levels and the ...

Spatiotemporal analysis of airborne pollutants and health risks in Mashhad metropolis: enhanced insights through sensitivity analysis and machine learning.

Environmental geochemistry and health
The study delved into an extensive assessment of outdoor air pollutant levels, focusing specifically on PM, SO, NO, and CO, across the Mashhad metropolis from 2017 to 2021. In tandem, it explored their intricate correlations with meteorological condi...

Predicting the risk of cardiovascular disease in adults exposed to heavy metals: Interpretable machine learning.

Ecotoxicology and environmental safety
Machine learning exhibits excellent performance in terms of predictive power. We aimed to construct an interpretable machine learning model utilizing National Health and Nutrition Examination Survey data to investigate the relationship between heavy ...

Spatiotemporal modeling of long-term PM concentrations and population exposure in Greece, using machine learning and statistical methods.

The Science of the total environment
The lack of high-resolution, long-term PM observations in Greece and the Eastern Mediterranean hampers the development of spatial models that are crucial for providing representative exposure estimates to health studies. This work presents a spatial ...

Uncovering global risk to human and ecosystem health from pesticides in agricultural surface water using a machine learning approach.

Environment international
Pesticides typically co-occur in agricultural surface waters and pose a potential threat to human and ecosystem health. As pesticide screening in global agricultural surface waters is an immense analytical challenge, a detailed risk picture of pestic...

IMPACT OF REAL-LIFE ENVIRONMENTAL EXPOSURES ON REPRODUCTION: A contemporary review of machine learning to predict adverse pregnancy outcomes from pharmaceuticals, including DDIs.

Reproduction (Cambridge, England)
IN BRIEF: Clinical drug trials often do not include pregnant people due to health risks; therefore, many medications have an unknown effect on the developing fetus. Machine learning QSAR models have been used successfully to predict the fetal risk of...

Machine learning model for age-related macular degeneration based on heavy metals: The National Health and Nutrition Examination Survey 2005 to 2008.

Scientific reports
Age-related macular degeneration (AMD) is the leading cause of blindness in older people in developed countries. It has been suggested that heavy metal exposure may be associated with the development of AMD, but most studies have focused on the effec...