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Foundation model based multimodal transformer framework for survival analysis in HER2 stratified breast cancer.

Physics in medicine and biology
. To improve survival prediction for HER2-positive breast cancer by integrating histopathological, molecular, and clinical data using a multimodal transformer framework.. We propose a multimodal transformer framework for breast cancer survival predic...

Maturation of Neuronal Activity in the Human Cortex Exhibits Robust Spatial Gradients across the Birth Transition.

The Journal of neuroscience : the official journal of the Society for Neuroscience
Early structural and molecular development of the human cortex is extensively studied, but little is known about the development of neuronal activity across cortical regions. We used dense array electroencephalography recordings and a machine learnin...

Construction and application of machine learning models for predicting intradialytic hypotension.

PloS one
INTRODUCTION: Intradialytic hypotension (IDH) remains a prevalent complication of hemodialysis, which is associated with adverse outcomes for patients. This study seeks to harness machine learning to construct predictive models for IDH based on multi...

Translation and validation of the artificial intelligence anxiety scale in German.

PloS one
AIM: Artificial intelligence anxiety refers to fear due to challenges caused by AI-related changes in one's own life. As the first study, our aim was to translate and validate the German version of the Artificial Intelligence Anxiety Scale (AIAS-G). ...

Discovering Biomarkers for Asymptomatic Tuberculosis via Olink Proteomics and Machine Learning.

Journal of proteome research
The diagnosis of asymptomatic tuberculosis (TB) remains challenging due to an early disease stage. This study aimed to identify and validate plasma biomarkers for asymptomatic TB by integrating the Olink proteomics with multiple machine learning algo...

Paired snRNA-seq and scRNA-seq analysis of MASLD patients to identify early-stage markers for disease progression.

Hepatology communications
BACKGROUND AND AIMS: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading cause of chronic liver disease worldwide. Progression from simple metabolic dysfunction-associated steatotic liver (MASL) without necro-inflammation to...

Artificial intelligence-assisted ultrasound screening for breast cancer in China: a prospective, clustered, controlled, population-based study.

Breast cancer research : BCR
INTRODUCTION: Breast cancer Mammography (MAM) screening was proven to improve survival worldwide. However, younger patients with higher breast density made MAM less effective in China. It is necessary to establish Chinese-specific effective screening...

A ternary-code DNA methylome atlas of mouse tissues.

Genome biology
BACKGROUND: DNA cytosine modifications, including 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC), are key epigenetic regulators with distinct functions. Dissecting the ternary code (C, 5mC, 5hmC) across tissues and cell types remains a cri...

Judgments of learning distinguish humans from large language models in predicting memory.

Scientific reports
Large language models (LLMs) increasingly mimic human cognition in various language-based tasks. However, their capacity for metacognition-particularly in predicting memory performance-remains unexplored. Here, we introduce a cross-agent prediction m...