BACKGROUND: Many supervised learning algorithms have been applied in deriving gene signatures for patient stratification from gene expression data. However, transferring the multi-gene signatures from one analytical platform to another without loss o...
AMIA ... Annual Symposium proceedings. AMIA Symposium
Nov 5, 2015
Brain glioma is the most common primary malignant brain tumors in adults with different pathologic subtypes: Lower Grade Glioma (LGG) Grade II, Lower Grade Glioma (LGG) Grade III, and Glioblastoma Multiforme (GBM) Grade IV. The survival and treatment...
BACKGROUND: Glioblastoma (GBM) is the most aggressive adult primary brain cancer, characterized by significant heterogeneity, posing challenges for patient management, treatment planning, and clinical trial stratification.
Purpose To develop and evaluate the performance of NNFit, a self-supervised deep learning method for quantification of high-resolution short-echo-time (TE) echo-planar spectroscopic imaging (EPSI) datasets, with the goal of addressing the computation...
This study aimed to investigate the genetic association between glioblastoma (GBM) and unsupervised deep learning-derived imaging phenotypes (UDIPs). We employed a combination of genome-wide association study (GWAS) data, single-nucleus RNA sequencin...
OBJECTIVE: Maximizing safe resection in neuro-oncology has become paramount to improving patient survival and outcomes. Laser interstitial thermal therapy (LITT) offers similar survival benefits to traditional resection, alongside shorter hospital st...
Purpose To develop and validate a deep learning (DL) method to detect and segment enhancing and nonenhancing cellular tumor on pre- and posttreatment MRI scans in patients with glioblastoma and to predict overall survival (OS) and progression-free su...
Studies in health technology and informatics
Aug 30, 2024
INTRODUCTION: Glioblastoma (GB) is one of the most aggressive tumors of the brain. Despite intensive treatment, the average overall survival (OS) is 15-18 months. Therefore, it is helpful to be able to assess a patient's OS to tailor treatment more s...
BACKGROUND: The extended acquisition times required for MRI limit its availability in resource-constrained settings. Consequently, accelerating MRI by undersampling k-space data, which is necessary to reconstruct an image, has been a long-standing bu...
Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences
Jan 28, 2024
OBJECTIVES: Glioblastoma (GBM) and brain metastases (BMs) are the two most common malignant brain tumors in adults. Magnetic resonance imaging (MRI) is a commonly used method for screening and evaluating the prognosis of brain tumors, but the specifi...