AIMC Topic: Glioma

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Enhanced glioma semantic segmentation using U-net and pre-trained backbone U-net architectures.

Scientific reports
Gliomas are known to have different sub-regions within the tumor, including the edema, necrotic, and active tumor regions. Segmenting of these regions is very important for glioma treatment decisions and management. This paper aims to demonstrate the...

Integration of Multi-omics Data Based on Deep Learning for Subtyping of Low-Grade Glioma.

Journal of molecular neuroscience : MN
Low-grade gliomas (LGGs) represent a complex and aggressive category of brain tumors. Despite recent advancements in molecular subtyping and characterization, the necessity to identify additional molecular subtypes and biomarkers remains. To delineat...

Machine Learning-Driven radiomics on 18 F-FDG PET for glioma diagnosis: a systematic review and meta-analysis.

Cancer imaging : the official publication of the International Cancer Imaging Society
BACKGROUND: Machine learning (ML) applied to radiomics has revolutionized neuro-oncological imaging, yet the diagnostic performance of ML models based specifically on ^18F-FDG PET features in glioma remains poorly characterized.

Optimized deep learning for brain tumor detection: a hybrid approach with attention mechanisms and clinical explainability.

Scientific reports
Brain tumor classification (BTC) from Magnetic Resonance Imaging (MRI) is a critical diagnosis task, which is highly important for treatment planning. In this study, we propose a hybrid deep learning (DL) model that integrates VGG16, an attention mec...

A novel residual network based on multidimensional attention and pinwheel convolution for brain tumor classification.

Scientific reports
Early and accurate brain tumor classification is vital for clinical diagnosis and treatment. Although Convolutional Neural Networks (CNNs) are widely used in medical image analysis, they often struggle to focus on critical information adequately and ...

An effective flowchart for multimodal brain tumor binary classification with ranked 3D texture features.

Scientific reports
Brain tumors have complex structures, and their shape, density, and size can vary widely. Consequently, their accurate classification, which involves identifying features that best describe the tumor data, is challenging. Using classical 2D texture f...

Machine learning-based construction of Immunogenic cell death-related score for improving prognosis and personalized treatment in glioma.

Scientific reports
Immunogenic cell death (ICD) is capable of activating both innate and adaptive immune responses. In this study, we aimed to develop an ICD-related signature in glioma patients and facilitate the assessment of their prognosis and drug sensitivity. Con...

Building simplified cancer subtyping and prediction models with glycan gene signatures.

Cell reports methods
We identified a gene panel comprising 71 glycosyltransferases (GTs) that alter glycan patterns on cancer cells as they become more virulent. When these cancer-pattern GTs (CPGTs) were run through an algorithm trained on The Cancer Genome Atlas, they ...

Multimodal radiomics in glioma: predicting recurrence in the peritumoural brain zone using integrated MRI.

BMC medical imaging
BACKGROUND: Gliomas exhibit a high recurrence rate, particularly in the peritumoural brain zone after surgery. This study aims to develop and validate a radiomics-based model using preoperative fluid-attenuated inversion recovery (FLAIR) and T1-weigh...

Phenotype augmentation using generative AI for isocitrate dehydrogenase mutation prediction in glioma.

Scientific reports
This study investigated the effects of feature augmentation, which uses generated images with specific imaging features, on the performance of isocitrate dehydrogenase (IDH) mutation prediction models in gliomas. A total of 598 patients were included...