AIMC Topic: Gold

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Gold nanorods as multidimensional optical nanomaterials: machine learning-enhanced quantitative fingerprinting of proteins for diagnostic applications.

Nanoscale
The rapid and precise quantification and identification of proteins as key diagnostic biomarkers hold significant promise in allergy testing, disease diagnosis, clinical treatment, and proteomics. This is crucial because alterations in disease-associ...

Addressing Hemolysis-Induced Loss of Sensitivity in Lateral Flow Assays of Blood Samples with Platinum-Coated Gold Nanoparticles and Machine Learning.

Analytical chemistry
Gold nanoparticles (GNPs), which appear red, are widely used as labels in lateral flow assays (LFAs) for visual detection. However, in blood-derived samples, hemolysis─caused by the rupture of red blood cells and the release of hemoglobin─creates a r...

Anticoagulation colloidal microrobots based on heparin-mimicking polymers.

Journal of colloid and interface science
Coagulation within blood vessels is a major cause of cardiovascular disease and global mortality, highlighting the urgent need for effective anticoagulant strategies. In this study, we introduce a dynamic and highly efficient anticoagulant platform, ...

Fluorescent sensor array for rapid bacterial identification using antimicrobial peptide-functionalized gold nanoclusters and machine learning.

Talanta
Bacterial infectious diseases pose significant challenges to public health, emphasizing the need for rapid and accurate diagnostic tools. Here, we introduced a multichannel fluorescent sensor array based on antimicrobial peptide-functionalized gold n...

A new approach to dilution prediction of underground mine gold using computing techniques.

Anais da Academia Brasileira de Ciencias
Controlling ore dilution in underground mining is challenging. In this study, data from a Brazilian gold mine were analyzed, covering 70 chambers and 26 variables. Six key variables were identified through decision tree analysis, forming the basis of...

Fast screening of COVID-19 inpatient samples by integrating machine learning and label-free SERS methods.

Analytica chimica acta
BACKGROUND: Advances in bio-analyte detection demonstrate the need for innovation to overcome the limitations of traditional methods. Emerging viruses evolve into variants, driving the need for fast screening to minimize the time required for positiv...

Rapid and Differential Diagnosis of Sepsis Stages Using an Advanced 3D Plasmonic Bimetallic Alloy Nanoarchitecture-Based SERS Biosensor Combined with Machine Learning for Multiple Analyte Identification.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Rapid and accurate differential diagnosis of infections, sepsis, and septic shock is essential for preventing unnecessary antibiotic overuse and improving the chance of patient survival. To address this, a 3D gold nanogranule decorated gold-silver al...

Dual-Mode Colorimetric/SERS Lateral Flow Immunoassay with Machine Learning-Driven Optimization for Ultrasensitive Mycotoxin Detection.

Analytical chemistry
Detecting and quantifying mycotoxins using LFIA are challenging due to the need for high sensitivity and accuracy. To address this, a dual-mode colorimetric-SERS LFIA was developed for detecting deoxynivalenol (DON). Rhodium nanocores provided strong...

Highly Sensitive and Interference-Free Detection of Multiple Drug Molecules in Serum Using Dual-Modified SERS Substrates Combined with AI Algorithm Analysis.

Analytical chemistry
Surface-enhanced Raman spectroscopy (SERS) technology has shown broad potential in drug concentration detection, but its application in blood drug monitoring faces significant challenges. The primary difficulty lies in overcoming the interference cau...

Neuro-computational simulation of blood flow loaded with gold and maghemite nanoparticles inside an electromagnetic microchannel under rapid and unexpected change in pressure gradient.

Electromagnetic biology and medicine
In cardiovascular research, electromagnetic fields generated by Riga plates are utilized to study or manipulate blood flow dynamics, which is particularly crucial in developing treatments for conditions such as arterial plaque deposition and understa...