AIMC Topic: Gout

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Development and validation of a multidimensional and interpretable artificial intelligence model to predict gout recurrence in hospitalised patients: a real-world, ambispective multicentre cohort study in China.

BMC medicine
BACKGROUND: Gout is the most common inflammatory arthritis. Recurrent flares are common among hospitalised patients and contribute to substantial clinical and economic burden. However, the accurate prediction of inpatient recurrence remains challengi...

Machine learning models for predicting renal injury in patients with gout.

Renal failure
BACKGROUND: Renal injury is a severe complication among individuals diagnosed with gout. This research constructed a machine learning predictive model to assess renal injury risk in gout patients.

Development and validation of risk prediction models for acute kidney disease in gout patients: a retrospective study using machine learning.

European journal of medical research
BACKGROUND: Limited research has been conducted on the prevalence of acute kidney injury (AKI) and acute kidney disease (AKD) in gout patients, as well as the impact of these renal complications on patient outcomes. This study aims to develop machine...

Interpretive prediction of hyperuricemia and gout patients via machine learning analysis of human gut microbiome.

BMC microbiology
Hyperuricemia (HUA) and gout result from imbalances in uric acid metabolism and are closely associated with the gut microbiota. Advanced analytical methods facilitate the exploration of microbiota complexity. In this study, 16S rRNA sequencing data f...

Assessment of drug induced hyperuricemia and gout risk using the FDA adverse event reporting system.

Scientific reports
Hyperuricemia, the key pathological basis of gout, is increasingly prevalent worldwide. While lifestyle factors contribute, various medications also play a role. However, their specific risks and mechanisms remain inadequately studied. Disproportiona...

Thinking Like Sonographers: Human-Centered CNN Models for Gout Diagnosis From Musculoskeletal Ultrasound.

IEEE transactions on bio-medical engineering
We explore the potential of deep convolutional neural network (CNN) models for differential diagnosis of gout from musculoskeletal ultrasound (MSKUS). Our exhaustive study of state-of-the-art (SOTA) CNN image classification models for this problem re...

Developing an interpretable machine learning model for diagnosing gout using clinical and ultrasound features.

European journal of radiology
OBJECTIVE: To develop a machine learning (ML) model using clinical data and ultrasound features for gout prediction, and apply SHapley Additive exPlanations (SHAP) for model interpretation.

Large language models for accurate disease detection in electronic health records: the examples of crystal arthropathies.

RMD open
OBJECTIVES: We propose and test a framework to detect disease diagnosis using a recent large language model (LLM), Meta's Llama-3-8B, on French-language electronic health record (EHR) documents. Specifically, it focuses on detecting gout ('goutte' in...

Multimodal Machine Learning-Based Marker Enables Early Detection and Prognosis Prediction for Hyperuricemia.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)
Hyperuricemia (HUA) has emerged as the second most prevalent metabolic disorder characterized by prolonged and asymptomatic period, triggering gout and metabolism-related outcomes. Early detection and prognosis prediction for HUA and gout are crucial...

Creating machine learning models that interpretably link systemic inflammatory index, sex steroid hormones, and dietary antioxidants to identify gout using the SHAP (SHapley Additive exPlanations) method.

Frontiers in immunology
BACKGROUND: The relationship between systemic inflammatory index (SII), sex steroid hormones, dietary antioxidants (DA), and gout has not been determined. We aim to develop a reliable and interpretable machine learning (ML) model that links SII, sex ...