Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2022
The APOE-ε4 allele is a known genetic risk for Alzheimer's disease (AD). Thus, it can be reasoned that the APOE-ε4 allele would also impact neurodegeneration-associated structural brain changes. Here we probe if the APOE-ε4 genotype directly modulate...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Nov 1, 2021
Deep brain nuclei are closely related to the pathogenesis of neurodegenerative diseases. Automatic segmentation for brain nuclei plays a significant role in aging and disease-related assessment. Quantitative susceptibility mapping (QSM), as a novel M...
Based on whole-brain gray matter volume (GMV), we used relevance vector regression to predict the Rey's Auditory Verbal Learning Test Delayed Recall (AVLT-DR) scores of individual amnestic mild cognitive impairment (aMCI) patient. The whole-brain GMV...
Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE-HS) is a common type of pediatric epilepsy. We sought to evaluate whether the combination of voxel-based morphometry (VBM) and support vector machine (SVM), a machine learning method, was...
Neurobiological heterogeneity in schizophrenia is poorly understood and confounds current analyses. We investigated neuroanatomical subtypes in a multi-institutional multi-ethnic cohort, using novel semi-supervised machine learning methods designed t...
Despite the high level of interest in the use of machine learning (ML) and neuroimaging to detect psychosis at the individual level, the reliability of the findings is unclear due to potential methodological issues that may have inflated the existing...
BACKGROUND: Because Alzheimer's Disease (AD) has very complicated pattern changes, it is difficult to evaluate it with a specific factor. Recently, novel machine learning methods have been applied to solve limitations.
Neuroanatomical pattern classification using support vector machines (SVMs) has shown promising results in classifying Multiple Sclerosis (MS) patients based on individual structural magnetic resonance images (MRI). To determine whether pattern class...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
Jul 1, 2019
In this paper, we proposed and validated a novel and fully automatic pipeline for simultaneous tissue classification and lateral ventricle segmentation via a 2D U-net. The 2D U-net was driven by a 3D fully convolutional neural network (FCN). Multiple...
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