AIMC Topic: Haplotypes

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Supervised machine learning reveals introgressed loci in the genomes of Drosophila simulans and D. sechellia.

PLoS genetics Apr 23, 2018
Hybridization and gene flow between species appears to be common. Even though it is clear that hybridization is widespread across all surveyed taxonomic groups, the magnitude and consequences of introgression are still largely unknown. Thus it is cru...
Software Computer Simulation Hybridization, Genetic Genetics, Population Drosophila Drosophila simulans Gene Flow Genetic Speciation Genome, Insect Genetic Variation Supervised Machine Learning Species Specificity Models, Genetic Animals Haplotypes Evolution, Molecular
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S/HIC: Robust Identification of Soft and Hard Sweeps Using Machine Learning.

PLoS genetics Mar 15, 2016
Detecting the targets of adaptive natural selection from whole genome sequencing data is a central problem for population genetics. However, to date most methods have shown sub-optimal performance under realistic demographic scenarios. Moreover, over...
Selection, Genetic Genetics, Population Genome, Human Genetic Drift Chromosomes, Human, Pair 18 Humans Haplotypes Machine Learning
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Sparse Inverse Covariance Estimation with L0 Penalty for Network Construction with Omics Data.

Journal of computational biology : a journal of computational molecular cell biology Feb 1, 2016
Constructing coexpression and association networks with omics data is crucial for studying gene-gene interactions and underlying biological mechanisms. In recent years, learning the structure of a Gaussian graphical model from high-dimensional data u...
Signal-To-Noise Ratio Epistasis, Genetic Haplotypes Genomics Animals Sequence Analysis, DNA Models, Genetic Humans Machine Learning
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[GENES ALLELE STATUS OF ANGIOTENSINCONVERTING ENZYME (I/D) AND ENDOTHELIAL NITRIC OXIDE SYNTHASE (894 G > T) IN PATIENTS WITH ACUTE CORONARY SYNDROME].

Likars'ka sprava Jan 1, 2015
The association of genes polymorphism of angiotensin-converting enzyme ACE (I/D) and endothelial nitric oxide synthase eNOS (894 G > T) with acute myocardial infarction (MI) among residents of North Bukovina region was evaluated. II/GG and ID/GG hapl...
Gene Frequency Coronary Vessels Nitric Oxide Synthase Type III Peptidyl-Dipeptidase A Male Haplotypes Alleles INDEL Mutation Middle Aged Acute Coronary Syndrome Prospective Studies Adult Aged, 80 and over Risk Factors Gene Expression Female Polymorphism, Single Nucleotide Case-Control Studies Myocardial Infarction Aged Humans
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