AIMC Topic: Humans

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A deep-learning model to predict the completeness of cytoreductive surgery in colorectal cancer with peritoneal metastasis☆.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology
BACKGROUND: Colorectal cancer (CRC) with peritoneal metastasis (PM) is associated with poor prognosis. The Peritoneal Cancer Index (PCI) is used to evaluate the extent of PM and to select Cytoreductive Surgery (CRS). However, PCI score is not accurat...

Dual-Modality Virtual Biopsy System Integrating MRI and MG for Noninvasive Predicting HER2 Status in Breast Cancer.

Academic radiology
RATIONALE AND OBJECTIVES: Accurate determination of human epidermal growth factor receptor 2 (HER2) expression is critical for guiding targeted therapy in breast cancer. This study aimed to develop and validate a deep learning (DL)-based decision-mak...

Nano biosensor unlocks tumor derived immune signals for the early detection of ovarian cancer.

Biosensors & bioelectronics
Ovarian cancer is a critical health issue for women nowadays. Its impact is significant because of its high mortality rate (324,603 worldwide), late-stage diagnosis and poor survival rate. Lack of screening tests, vague symptoms, misdiagnosis, and ag...

Optimization of primary screw stability in Trabecular bone using neural network-based models.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: Screw implant stability in bone is crucial to the success of many orthopaedic procedures, yet the relationship between screw design parameters and specific bone characteristics remains underexplored. This study aims to optim...

Post-Bariatric Hypoglycemia After Gastric Bypass: Clinical Characteristics, Risk Factors, and Future Directions-A Response to Grover et al.

Clinical endocrinology
BACKGROUND: Post-bariatric hypoglycemia (PBH) after Roux-en-Y gastric bypass (RYGB) is a complex complication, often characterized by potentially severe hypoglycemic episodes and reduced hypoglycemia awareness. Recent findings suggest that autonomic ...

Innovative construction and application of bile duct organoids: Unraveling the complexity of bile duct diseases and potential therapeutic strategies.

Cancer letters
The biliary system is crucial for liver function, regulating bile production, secretion, and transport. Dysfunctions within this system can lead to various diseases, such as cholangiopathies and biliary fibrosis, which may progress from benign to mal...

Mapping human fingerprint beyond level-3 based on an amphiphilic aggregation-induced emission luminogen and the construction of intelligent platform for personal identification.

Analytica chimica acta
BACKGROUND: Fluorescence imaging agents have been benefiting tremendously from tailor-made aggregation-induced emission (AIE) luminogens, owing to their high on-off ratio, large signal contrast, low background noise as well as the resistance to photo...

Biochemical Characterization of Disease-Associated Variants of Human Ornithine Transcarbamylase.

ACS chemical biology
Human ornithine transcarbamylase deficiency (OTCD) is the most common ureagenesis disorder in the world. OTCD is an X-linked genetic deficiency in which patients experience hyperammonemia to varying degrees depending on the severity of the genetic mu...

Comparing neural language models for medical concept representation and patient trajectory prediction.

Artificial intelligence in medicine
Effective representation of medical concepts is crucial for secondary analyses of electronic health records. Neural language models have shown promise in automatically deriving medical concept representations from clinical data. However, the comparat...

Artificial intelligence: Friend or foe in the assessment of dental students?

Journal of dentistry
OBJECTIVES: Incorporating artificial intelligence (AI) in assessing dental students' knowledge and skills is in its infancy, despite AI being well established as an aid to aspects of clinical diagnosis and education. This study aimed to investigate w...