Nuclear Magnetic Resonance (NMR) spectroscopy is a powerful tool for analyzing complex mixtures due to its ability to manage matrix complexity, provide detailed molecular insights, and preserve sample integrity. In metabolomics, NMR enables the ident...
BACKGROUND: Newborn screening (NBS) enables early detection of metabolic disorders, but current tandem mass spectrometry (MS/MS) methods often lead to false positives and require confirmatory testing, causing diagnostic delays. We evaluated whether i...
BACKGROUND: In recent years, several studies have explored the use of large language models (LLMs) such as ChatGPT-4, Claude, Gemini Advanced, and DeepSeek-R1 in dental education. Nevertheless, no study has yet reported a comparative evaluation of mu...
BACKGROUND: Large Language Models (LLMs) such as ChatGPT and Google Gemini are increasingly explored for their potential in patient education, particularly in the perioperative setting. As text-based tools trained on extensive datasets, they can gene...
Predicting protein‒protein interactions (PPIs) plays a crucial role in understanding biological processes. Although biological experimental methods can identify PPIs, they are costly, time-consuming, labor-intensive, and often lack stability. In cont...
BACKGROUND: Single-cell RNA sequencing (scRNA-seq) provides extensive opportunities to explore cellular heterogeneity but is often limited by substantial technical noise and variability. The prevalence of zero counts, arising from both biological var...
Optical coherence tomography (OCT) has a wide range of applications in the diagnosis and treatment of diseases such as heart and ophthalmic diseases. However, the inherent limitations of imaging hardware, low spatial sampling rates, and noise severel...
Biomedical physics & engineering express
Nov 19, 2025
Artificial intelligence (AI) systems are increasingly used in medical imaging for disease diagnosis, yet their vulnerability to adversarial attacks poses significant risks for clinical deployment. In this work, we systematically evaluate the suscepti...
Positron imaging has shown great potential in industrial non-destructive testing due to its high sensitivity and ability to reveal internal structures of complex components. However, reconstructing high-quality images from positron emission data rema...
BACKGROUND: Parkinson's disease is a movement disorder featuring motor symptoms and cognitive decline, which can manifest as mild cognitive impairment. The incidence of mild cognitive impairment increases with disease progression, and Parkinson's dis...
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