AIMC Topic: Humans

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Cardiovascular risk in psoriatic arthritis: How can we manage it?

Autoimmunity reviews
It is now widely recognized that patients with psoriatic arthritis (PsA) have a higher risk of cardiovascular disease (CVD) when compared with the general population. A number of factors contribute to this increased risk. Skin and articular inflammat...

Technological innovations promote cancer stem cell-based translational research.

Cancer letters
Cancer remains one of the leading causes of death worldwide, with therapy resistance and tumor recurrence driven by a subpopulation of cells known as cancer stem cells (CSCs). CSCs possess a remarkable ability to evade apoptosis, adapt to harsh micro...

Calcium ion dynamic trajectory is associated with prognosis in patients with sepsis: A potential class mixture modeling study.

International immunopharmacology
Disturbed calcium homeostasis in patients with sepsis is associated with poor prognosis; however, its dynamic pattern and clinical significance remain unclear. This study aimed to establish an early warning system for calcium homeostasis in sepsis by...

Development and application of an AI-empowered acoustic monitoring system for misuse detection in dry powder inhalers.

International journal of pharmaceutics
Misuse and poor inhalation techniques remain persistent issues in pulmonary drug delivery via dry powder inhalation. While acoustic-based monitoring has been a feasible strategy, existing approaches often depend on smartphones for signal collection, ...

Integrating machine learning and metabolomics to uncover new biomarkers for predicting pesticide exposure among patients with kidney function decline.

The Science of the total environment
Although pesticide application is indispensable for agricultural productivity, improper use can pose significant health risks, particularly for vulnerable populations. This study investigated the effects of pesticide exposure on metabolic pathways an...

Discrepancies between plantar pressure devices: Evaluating cross-system reliability for biomechanics, clinical use and predictive modelling.

Foot (Edinburgh, Scotland)
Plantar pressure measurement systems are widely used to assess foot function and gait, yet discrepancies in sensor design, measurement protocols, and population characteristics can undermine data comparability. This study investigated three platform‑...

Can GPT-4 provide human-level emotion support? Insights from machine learning-based evaluation framework.

Computers in biology and medicine
The global shortage of mental health services has sparked considerable interest in leveraging generative artificial intelligence (AI) to address psychological health challenges. This study systematically evaluates the emotional support capabilities o...

A practical approach to predicting long-term outcomes in traumatic brain injury: Enhancing clinical decision-making with machine learning.

Computers in biology and medicine
BACKGROUND: Traumatic brain injury (TBI) is among the most prevalent causes of emergency department visits globally. TBI leads to high morbidity and mortality rates, which poses a noteworthy burden on the medical system regarding both patients and ec...

Normal Pressure Hydrocephalus Classification using Weakly-Supervised Local Feature Extraction.

Computers in biology and medicine
Normal Pressure Hydrocephalus (NPH) presents diagnostic challenges because its symptoms often overlap with other neurological conditions. A key radiological NPH indicator is ventricular cerebrospinal fluid (CSF) volume, assessed by neuroradiologists ...

EmiNet: Moving bacteria detection on optical endomicroscopy images trained on synthetic data.

Computers in biology and medicine
Pneumonia, a respiratory disease often caused by bacterial infection in the distal lung, necessitates prompt and precise diagnosis, particularly in critical care settings. Optical endomicroscopy (OEM) facilitates real-time acquisition of in vivo and ...