AIMC Topic: Humans

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DeepTCR is a deep learning framework for revealing sequence concepts within T-cell repertoires.

Nature communications
Deep learning algorithms have been utilized to achieve enhanced performance in pattern-recognition tasks. The ability to learn complex patterns in data has tremendous implications in immunogenomics. T-cell receptor (TCR) sequencing assesses the diver...

Explaining decisions of graph convolutional neural networks: patient-specific molecular subnetworks responsible for metastasis prediction in breast cancer.

Genome medicine
BACKGROUND: Contemporary deep learning approaches show cutting-edge performance in a variety of complex prediction tasks. Nonetheless, the application of deep learning in healthcare remains limited since deep learning methods are often considered as ...

Diagnosis prediction of tumours of unknown origin using ImmunoGenius, a machine learning-based expert system for immunohistochemistry profile interpretation.

Diagnostic pathology
BACKGROUND: Immunohistochemistry (IHC) remains the gold standard for the diagnosis of pathological diseases. This technique has been supporting pathologists in making precise decisions regarding differential diagnosis and subtyping, and in creating p...

Artificial intelligence-aided CT segmentation for body composition analysis: a validation study.

European radiology experimental
BACKGROUND: Body composition is associated with survival outcome in oncological patients, but it is not routinely calculated. Manual segmentation of subcutaneous adipose tissue (SAT) and muscle is time-consuming and therefore limited to a single CT s...

Fully-automated global and segmental strain analysis of DENSE cardiovascular magnetic resonance using deep learning for segmentation and phase unwrapping.

Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
BACKGROUND: Cardiovascular magnetic resonance (CMR) cine displacement encoding with stimulated echoes (DENSE) measures heart motion by encoding myocardial displacement into the signal phase, facilitating high accuracy and reproducibility of global an...

Automated remote decision-making algorithm as a primary triage system using machine learning techniques.

Physiological measurement
OBJECTIVE: An objective and convenient primary triage procedure is needed for prioritizing patients who need help in mass casualty incident (MCI) situations, where there is a lack of medical staff and available resources. This study aimed to develop ...

Meniscal lesion detection and characterization in adult knee MRI: A deep learning model approach with external validation.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)
PURPOSE: Evaluation of a deep learning approach for the detection of meniscal tears and their characterization (presence/absence of migrated meniscal fragment).

Excitatory-inhibitory tone shapes decision strategies in a hierarchical neural network model of multi-attribute choice.

PLoS computational biology
We are constantly faced with decisions between alternatives defined by multiple attributes, necessitating an evaluation and integration of different information sources. Time-varying signals in multiple brain areas are implicated in decision-making; ...

Using Machine Learning to Unravel the Value of Radiographic Features for the Classification of Bone Tumors.

BioMed research international
OBJECTIVES: To build and validate random forest (RF) models for the classification of bone tumors based on the conventional radiographic features of the lesion and patients' clinical characteristics, and identify the most essential features for the c...

A Systematic Approach for MRI Brain Tumor Localization and Segmentation Using Deep Learning and Active Contouring.

Journal of healthcare engineering
One of the main requirements of tumor extraction is the annotation and segmentation of tumor boundaries correctly. For this purpose, we present a threefold deep learning architecture. First, classifiers are implemented with a deep convolutional neura...