The spine journal : official journal of the North American Spine Society
Feb 2, 2021
BACKGROUND CONTEXT: Accurately predicting the survival of patients with spinal metastases is important for guiding surgical intervention. The SORG machine-learning (ML) algorithm for the 90-day and one-year mortality of patients with metastatic cance...
Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
Feb 2, 2021
Biohybrid robotics is a field in which biological entities are combined with artificial materials in order to obtain improved performance or features that are difficult to mimic with hand-made materials. Three main level of integration can be envisio...
Proteins often exert their function by binding to other cellular partners. The hot spots are key residues for protein-protein binding. Their identification may shed light on the impact of disease associated mutations on protein complexes and help des...
Protein structure prediction is a long-standing unsolved problem in molecular biology that has seen renewed interest with the recent success of deep learning with AlphaFold at CASP13. While developing and evaluating protein structure prediction metho...
BACKGROUND: Chest X-ray radiography (CXR) has been widely considered as an accessible, feasible, and convenient method to evaluate suspected patients' lung involvement during the COVID-19 pandemic. However, with the escalating number of suspected cas...
Mental health concerns, such as suicidal thoughts, are frequently documented by providers in clinical notes, as opposed to structured coded data. In this study, we evaluated weakly supervised methods for detecting "current" suicidal ideation from uns...
Background The solid portion size of lung cancer lesions manifesting as subsolid lesions is key in their management, but the automatic measurement of such lesions by means of a deep learning (DL) algorithm needs evaluation. Purpose To evaluate the pe...
International journal of pharmaceutics
Feb 2, 2021
Drug development is time-consuming and inherently possesses a high failure rate. Pharmaceutical formulation development is the bridge that links a new chemical entity (NCE) to pre-clinical and clinical trials, and has a high impact on the efficacy an...
PURPOSE: Accurate clinical diagnosis of lymph node metastases is of paramount importance in the treatment of patients with abdominopelvic malignancy. This review assesses the diagnostic performance of deep learning algorithms and radiomics models for...
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