AIMC Topic: Humans

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Physicochemical stability of an admixture of lidocaine and ketamine in polypropylene syringe used in opioid-free anaesthesia.

European journal of hospital pharmacy : science and practice
OBJECTIVES: Opioid-free anaesthesia is a treatment strategy of pain management based on the use of drugs such as lidocaine, ketamine and dexmedetomidine that do not interact significantly with opioid receptors. In particular, these drugs are used by ...

Investigating Risk Factors and Predicting Complications in Deep Brain Stimulation Surgery with Machine Learning Algorithms.

World neurosurgery
BACKGROUND: Deep brain stimulation (DBS) surgery is an option for patients experiencing medically resistant neurologic symptoms. DBS complications are rare; finding significant predictors requires a large number of surgeries. Machine learning algorit...

Motion-corrected coronary calcium scores by a convolutional neural network: a robotic simulating study.

European radiology
OBJECTIVE: To classify motion-induced blurred images of calcified coronary plaques so as to correct coronary calcium scores on nontriggered chest CT, using a deep convolutional neural network (CNN) trained by images of motion artifacts.

Training for Walking Efficiency With a Wearable Hip-Assist Robot in Patients With Stroke: A Pilot Randomized Controlled Trial.

Stroke
Background and Purpose- The purpose of this study was to investigate the effects of gait training with a newly developed wearable hip-assist robot on locomotor function and efficiency in patients with chronic stroke. Methods- Twenty-eight patients wi...

Electronic Skin for Closed-Loop Systems.

ACS nano
Electronic skin (e-skin) uses advanced electronics and sensor arrays to manufacture human-skin-like robotics skin. The creation of e-skin has been made possible due to various physics effects/mechanisms, innovative materials, structural designs, and ...

Building brain-inspired computing.

Nature communications
Dmitri Strukov (an electrical engineer, University of California at Santa Barbara), Giacomo Indiveri (an electrical engineer, University of Zurich), Julie Grollier (a material physicist, Unite Mixte de Physique CNRS) and Stefano Fusi (a neuroscientis...

Computational methods and tools for binding site recognition between proteins and small molecules: from classical geometrical approaches to modern machine learning strategies.

Journal of computer-aided molecular design
In the current "genomic era" the number of identified genes is growing exponentially. However, the biological function of a large number of the corresponding proteins is still unknown. Recognition of small molecule ligands (e.g., substrates, inhibito...