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Optimized generation of high-resolution phantom images using cGAN: Application to quantification of Ki67 breast cancer images.

PloS one
In pathology, Immunohistochemical staining (IHC) of tissue sections is regularly used to diagnose and grade malignant tumors. Typically, IHC stain interpretation is rendered by a trained pathologist using a manual method, which consists of counting e...

Machine learning in chemoinformatics and drug discovery.

Drug discovery today
Chemoinformatics is an established discipline focusing on extracting, processing and extrapolating meaningful data from chemical structures. With the rapid explosion of chemical 'big' data from HTS and combinatorial synthesis, machine learning has be...

Deep neural networks for automatic detection of osteoporotic vertebral fractures on CT scans.

Computers in biology and medicine
Osteoporotic vertebral fractures (OVFs) are prevalent in older adults and are associated with substantial personal suffering and socio-economic burden. Early diagnosis and treatment of OVFs are critical to prevent further fractures and morbidity. How...

Autonomous Magnetic Microrobots by Navigating Gates for Multiple Biomolecules Delivery.

Small (Weinheim an der Bergstrasse, Germany)
The precise delivery of biofunctionalized matters is of great interest from the fundamental and applied viewpoints. In spite of significant progress achieved during the last decade, a parallel and automated isolation and manipulation of rare analyte,...

Model-based and Model-free Machine Learning Techniques for Diagnostic Prediction and Classification of Clinical Outcomes in Parkinson's Disease.

Scientific reports
In this study, we apply a multidisciplinary approach to investigate falls in PD patients using clinical, demographic and neuroimaging data from two independent initiatives (University of Michigan and Tel Aviv Sourasky Medical Center). Using machine l...

Machine learning identifies signatures of host adaptation in the bacterial pathogen Salmonella enterica.

PLoS genetics
Emerging pathogens are a major threat to public health, however understanding how pathogens adapt to new niches remains a challenge. New methods are urgently required to provide functional insights into pathogens from the massive genomic data sets no...

Sharpening of Hierarchical Visual Feature Representations of Blurred Images.

eNeuro
The robustness of the visual system lies in its ability to perceive degraded images. This is achieved through interacting bottom-up, recurrent, and top-down pathways that process the visual input in concordance with stored prior information. The inte...

Convolutional neural network-based classification system design with compressed wireless sensor network images.

PloS one
With the introduction of various advanced deep learning algorithms, initiatives for image classification systems have transitioned over from traditional machine learning algorithms (e.g., SVM) to Convolutional Neural Networks (CNNs) using deep learni...
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Unobtrusive Activity Recognition of Elderly People Living Alone Using Anonymous Binary Sensors and DCNN.

IEEE journal of biomedical and health informatics
Elderly population (over the age of 60) is predicted to be 1.2 billion by 2025. Most of the elderly people would like to stay alone in their own house due to the high eldercare cost and privacy invasion. Unobtrusive activity recognition is the most p...
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