Humans

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Synergism of prenylflavonoids from Morus alba root bark against clinical MRSA isolates.

Phytomedicine : international journal of phytotherapy and phytopharmacology Dec 21, 2017
BACKGROUND: Clinical methicillin-resistant Staphylococcus aureus (MRSA) is a thorny problem in current anti-infective therapeutics and a challenge of new drug development. Plant prenylflavonoids possess anti-MRSA activity, but few of the prenylflavon...
Plant Bark Anti-Bacterial Agents Plant Roots Microbial Sensitivity Tests Humans Morus Methicillin-Resistant Staphylococcus aureus Aminoglycosides Drug Synergism Drug Therapy, Combination Methicillin Cell Line Vancomycin Flavonoids
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Human Wharton's Jelly-Derived Stem Cells Display a Distinct Immunomodulatory and Proregenerative Transcriptional Signature Compared to Bone Marrow-Derived Stem Cells.

Stem cells and development Dec 21, 2017
Mesenchymal stromal cells (MSCs) are multipotent stem cells with immunosuppressive and trophic support functions. While MSCs from different sources frequently display a similar appearance in culture, they often show differences in their surface marke...
Humans Gene Expression Regulation Cell Proliferation Immunomodulation Gene Expression Profiling Mesenchymal Stem Cells Gene Ontology Cell Line, Tumor Bone Marrow Cells Cell Adhesion
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Apolipoprotein A-I: A favorable prognostic marker in infective endocarditis.

Journal of clinical lipidology Dec 21, 2017
BACKGROUND: Decreased apolipoprotein A-I (apoA-I) and high-density lipoprotein cholesterol (HDL-C) are common in inflammation and sepsis. No study with a large sample size has been performed to investigate the prognostic value of apoA-I or HDL-C in i...
Logistic Models Apolipoprotein A-I Cholesterol, HDL Endocarditis Male Middle Aged Humans Hospital Mortality Biomarkers Prognosis Female Adult
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Bayesian averaging over Decision Tree models for trauma severity scoring.

Artificial intelligence in medicine Dec 21, 2017
Health care practitioners analyse possible risks of misleading decisions and need to estimate and quantify uncertainty in predictions. We have examined the "gold" standard of screening a patient's conditions for predicting survival probability, based...
Humans Artificial Intelligence Decision Support Techniques Wounds and Injuries Markov Chains Injury Severity Score Monte Carlo Method Risk Assessment Decision Support Systems, Clinical Logistic Models Predictive Value of Tests Bayes Theorem United States Decision Trees Female Risk Factors Male Databases, Factual Prognosis Clinical Decision-Making
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[Surveillance of Sensitivity to Penicillin in streptococcus Agalactiae recovered from pregnant women between 35-37 weeks of gestation].

Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) Dec 21, 2017
Streptococcus agalactiae (GBS) cause severe infections in newborns under three months. Meningitis, pneumonia and sepsis are the main infectious diseases in these children. These infections are among the most serious that an individual can suffer in h...
Streptococcus agalactiae Penicillin Resistance Penicillins Pregnancy Trimester, Third Animals Humans Microbial Sensitivity Tests Pregnancy Streptococcal Infections Female
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Classifying cancer genome aberrations by their mutually exclusive effects on transcription.

BMC medical genomics Dec 21, 2017
BACKGROUND: Malignant tumors are typically caused by a conglomeration of genomic aberrations-including point mutations, small insertions, small deletions, and large copy-number variations. In some cases, specific chemotherapies and targeted drug trea...
Machine Learning Neoplasms Humans Genome, Human Transcription, Genetic Lung Neoplasms Adenocarcinoma Mutation
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Ontology-based systematic representation and analysis of traditional Chinese drugs against rheumatism.

BMC systems biology Dec 21, 2017
BACKGROUND: Rheumatism represents any disease condition marked with inflammation and pain in the joints, muscles, or connective tissues. Many traditional Chinese drugs have been used for a long time to treat rheumatism. However, a comprehensive infor...
Medicine, Chinese Traditional Knowledge Bases Semantics Biological Ontologies Rheumatic Diseases Humans
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Hadamard Kernel SVM with applications for breast cancer outcome predictions.

BMC systems biology Dec 21, 2017
BACKGROUND: Breast cancer is one of the leading causes of deaths for women. It is of great necessity to develop effective methods for breast cancer detection and diagnosis. Recent studies have focused on gene-based signatures for outcome predictions....
Computational Biology Support Vector Machine Prognosis Breast Neoplasms ROC Curve Humans Databases, Factual
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Comparison, alignment, and synchronization of cell line information between CLO and EFO.

BMC bioinformatics Dec 21, 2017
BACKGROUND: The Experimental Factor Ontology (EFO) is an application ontology driven by experimental variables including cell lines to organize and describe the diverse experimental variables and data resided in the EMBL-EBI resources. The Cell Line ...
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Biological Ontologies Cell Physiological Phenomena Algorithms Databases, Factual Gene Expression Profiling Data Mining Semantics Computational Biology Cell Line Humans
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Cell ontology in an age of data-driven cell classification.

BMC bioinformatics Dec 21, 2017
BACKGROUND: Data-driven cell classification is becoming common and is now being implemented on a massive scale by projects such as the Human Cell Atlas. The scale of these efforts poses a challenge. How can the results be made searchable and accessib...
Databases, Factual Animals Mice Humans Cells Computational Biology Models, Statistical Biological Ontologies
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