Annals of the Royal College of Surgeons of England
Apr 3, 2025
INTRODUCTION: Every patient admitted to hospital should receive a discharge letter when they leave. Artificial intelligence (AI) has the capability to fulfil this task. Here, we investigate the use of AI to generate discharge letters compared with le...
Dihydroorotate dehydrogenase (DHODH) is a key enzyme in pyrimidine biosynthesis, making it an attractive drug target for cancer, autoimmune diseases, and infections. Traditional DHODH inhibitor discovery is slow and costly. Our study integrated machi...
OBJECTIVES: To evaluate the added value of the late gadolinium enhancement (LGE)-scar radiomics features in predicting reverse left ventricular remodeling (r-LVR) in ST-segment elevation myocardial infarction (STEMI) patients using machine learning (...
BACKGROUND: This study aimed to preoperatively predict Ki-67 proliferation levels in patients with pancreatic solid pseudopapillary neoplasm (pSPN) using radiomics features extracted from arterial phase helical CT images.
Automated sleep staging on wearable data could improve our understanding and management of epilepsy. This study evaluated sleep scoring by a deep learning model on 223 night-sleep recordings from 50 patients measured in the hospital with an electroen...
Dysfunction in emotion regulation (ER) and autobiographical memory are components of major depressive disorder (MDD). However, little is known about how they mechanistically interact with mood disturbances in real time. Using machine learning-based n...
Interdisciplinary sciences, computational life sciences
Apr 3, 2025
Accurately identifying cell types in single-cell RNA sequencing data is critical for understanding cellular differentiation and pathological mechanisms in downstream analysis. As traditional biological approaches are laborious and time-intensive, it ...
BACKGROUND: We previously demonstrated the novel concept of using the integrated pressurized volume (IPV) with high-resolution anorectal manometry (HRAM) and found that it was predictive of delayed balloon expulsion (BE) test results. However, previo...
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