AIMC Topic: Hydroxyethyl Starch Derivatives

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Postoperative Acute Kidney Injury and Blood Product Transfusion After Synthetic Colloid Use During Cardiac Surgery.

Journal of cardiothoracic and vascular anesthesia Dec 28, 2016
OBJECTIVES: This study assessed the effect of 2 types of hydroxyethyl starches (HES) on renal integrity and blood transfusion in cardiac surgery patients.
Postoperative Complications Cardiac Surgical Procedures Colloids Female Humans Intraoperative Care Aged Retrospective Studies Erythrocyte Transfusion Male Acute Kidney Injury Hydroxyethyl Starch Derivatives Middle Aged Plasma Substitutes
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Minimum effective fluid volume of colloid to prevent hypotension during caesarean section under spinal anesthesia using a prophylactic phenylephrine infusion: An up-down sequential allocation study.

Journal of clinical anesthesia Dec 5, 2016
STUDY OBJECTIVE: The aim of this study was to de termine the minimum effective fluid volume (MEFV) of hydroxyethyl starch 130/0.4 (HES) infused in a preload fashion which would prevent hypotension in 50% of parturients undergoing caesarean section. A...
Hydroxyethyl Starch Derivatives Vasoconstrictor Agents Cesarean Section Fluid Therapy Humans Cardiac Output Parity Anesthesia, Spinal Pregnancy Anesthesia, Obstetrical Pregnancy Outcome Hypotension Female Phenylephrine Double-Blind Method
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Markers of endothelial damage and coagulation impairment in patients with severe sepsis resuscitated with hydroxyethyl starch 130/0.42 vs Ringer acetate.

Journal of critical care Dec 8, 2015
PURPOSE: The Scandinavian Starch for Severe Sepsis/Septic Shock (6S) trial showed increased mortality in patients resuscitated with hydroxyethyl starch 130/0.42 (HES) vs Ringer acetate. Different effects of the fluids on the endothelium may have cont...
Humans Adult Male Middle Aged Sepsis Biomarkers Female Aged Hydroxyethyl Starch Derivatives Plasma Substitutes Resuscitation Thrombomodulin Logistic Models Plasminogen Activator Inhibitor 1 Treatment Outcome Linear Models Blood Coagulation Odds Ratio Isotonic Solutions
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Hydroxyethyl Starch 130/0.4 and the Risk of Acute Kidney Injury After Cardiopulmonary Bypass: A Single-Center Retrospective Study.

Journal of cardiothoracic and vascular anesthesia Oct 19, 2015
OBJECTIVES: To investigate whether using hydroxyethyl starch (HES) 130/0.4 as a pump prime and for intraoperative fluid therapy is associated with postoperative acute kidney injury (AKI) after adult cardiac surgery.
Humans Male Retrospective Studies Middle Aged Isotonic Solutions Acute Kidney Injury Fluid Therapy Female Postoperative Complications Crystalloid Solutions Aged Cardiopulmonary Bypass Severity of Illness Index Intraoperative Care Aged, 80 and over Postoperative Period Hydroxyethyl Starch Derivatives
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Effects of tibial intraosseous and intravenous administration of Hextend on time of administration and hemodynamics in a hypovolemic swine model.

American journal of disaster medicine Jan 1, 2016
OBJECTIVE: To determine if there were significant differences between the tibial intraosseous (TIO) and intravenous (IV) administration of Hextend relative to time and in hemodynamics in a hypovolemic model.
Time Factors Treatment Outcome Infusions, Intravenous Fluid Therapy Heart Rate Shock Tibia Male Stroke Volume Swine Hypovolemia Prospective Studies Hemodynamics Infusions, Intraosseous Animals Systole Arterial Pressure Diastole Sus scrofa Random Allocation Hydroxyethyl Starch Derivatives Cardiac Output Plasma Substitutes
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Effects of intravenous, sternal, and humerus intraosseous administration of Hextend on time of administration and hemodynamics in a hypovolemic swine model.

American journal of disaster medicine Jan 1, 2016
OBJECTIVE: To determine if there were significant differences among humerus intraosseous (HIO), sternal intraosseous (SIO), and intravenous (IV) administration of 500 mL Hextend in hemodynamics or administration time in a hypovolemic swine model.
Sternum Diastole Humerus Plasma Substitutes Hypovolemia Infusions, Intraosseous Heart Rate Shock Random Allocation Cardiac Output Disease Models, Animal Systole Prospective Studies Infusions, Intravenous Sus scrofa Animals Blood Pressure Hydroxyethyl Starch Derivatives Male Fluid Therapy Stroke Volume Swine Hemodynamics Treatment Outcome
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