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Hydroxyethyl Starch Derivatives

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Postoperative Acute Kidney Injury and Blood Product Transfusion After Synthetic Colloid Use During Cardiac Surgery.

Journal of cardiothoracic and vascular anesthesia 28302346
OBJECTIVES: This study assessed the effect of 2 types of hydroxyethyl starches (HES) on renal integrity and blood transfusion in cardiac surgery patients.
Acute Kidney Injury Aged Cardiac Surgical Procedures Colloids Erythrocyte Transfusion Female Humans Hydroxyethyl Starch Derivatives Intraoperative Care Male Middle Aged Plasma Substitutes Postoperative Complications Retrospective Studies
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Minimum effective fluid volume of colloid to prevent hypotension during caesarean section under spinal anesthesia using a prophylactic phenylephrine infusion: An up-down sequential allocation study.

Journal of clinical anesthesia 28183565
STUDY OBJECTIVE: The aim of this study was to de termine the minimum effective fluid volume (MEFV) of hydroxyethyl starch 130/0.4 (HES) infused in a preload fashion which would prevent hypotension in 50% of parturients undergoing caesarean section. A...
Anesthesia, Obstetrical Anesthesia, Spinal Cardiac Output Cesarean Section Double-Blind Method Female Fluid Therapy Humans Hydroxyethyl Starch Derivatives Hypotension Parity Phenylephrine Pregnancy Pregnancy Outcome Vasoconstrictor Agents
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Effects of tibial intraosseous and intravenous administration of Hextend on time of administration and hemodynamics in a hypovolemic swine model.

American journal of disaster medicine 28134418
OBJECTIVE: To determine if there were significant differences between the tibial intraosseous (TIO) and intravenous (IV) administration of Hextend relative to time and in hemodynamics in a hypovolemic model.
Animals Arterial Pressure Cardiac Output Diastole Fluid Therapy Heart Rate Hemodynamics Hydroxyethyl Starch Derivatives Hypovolemia Infusions, Intraosseous Infusions, Intravenous Male Plasma Substitutes Prospective Studies Random Allocation Shock Stroke Volume Sus scrofa Swine Systole Tibia Time Factors Treatment Outcome
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Effects of intravenous, sternal, and humerus intraosseous administration of Hextend on time of administration and hemodynamics in a hypovolemic swine model.

American journal of disaster medicine 28134417
OBJECTIVE: To determine if there were significant differences among humerus intraosseous (HIO), sternal intraosseous (SIO), and intravenous (IV) administration of 500 mL Hextend in hemodynamics or administration time in a hypovolemic swine model.
Animals Blood Pressure Cardiac Output Diastole Disease Models, Animal Fluid Therapy Heart Rate Hemodynamics Humerus Hydroxyethyl Starch Derivatives Hypovolemia Infusions, Intraosseous Infusions, Intravenous Male Plasma Substitutes Prospective Studies Random Allocation Shock Sternum Stroke Volume Sus scrofa Swine Systole Treatment Outcome
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Markers of endothelial damage and coagulation impairment in patients with severe sepsis resuscitated with hydroxyethyl starch 130/0.42 vs Ringer acetate.

Journal of critical care 26810483
PURPOSE: The Scandinavian Starch for Severe Sepsis/Septic Shock (6S) trial showed increased mortality in patients resuscitated with hydroxyethyl starch 130/0.42 (HES) vs Ringer acetate. Different effects of the fluids on the endothelium may have cont...
Adult Aged Biomarkers Blood Coagulation Female Humans Hydroxyethyl Starch Derivatives Isotonic Solutions Linear Models Logistic Models Male Middle Aged Odds Ratio Plasma Substitutes Plasminogen Activator Inhibitor 1 Resuscitation Sepsis Thrombomodulin Treatment Outcome
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Hydroxyethyl Starch 130/0.4 and the Risk of Acute Kidney Injury After Cardiopulmonary Bypass: A Single-Center Retrospective Study.

Journal of cardiothoracic and vascular anesthesia 26774199
OBJECTIVES: To investigate whether using hydroxyethyl starch (HES) 130/0.4 as a pump prime and for intraoperative fluid therapy is associated with postoperative acute kidney injury (AKI) after adult cardiac surgery.
Acute Kidney Injury Aged Aged, 80 and over Cardiopulmonary Bypass Crystalloid Solutions Female Fluid Therapy Humans Hydroxyethyl Starch Derivatives Intraoperative Care Isotonic Solutions Male Middle Aged Postoperative Complications Postoperative Period Retrospective Studies Severity of Illness Index
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