AI Medical Compendium Topic

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Large Language Models

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Utility of word embeddings from large language models in medical diagnosis.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: This study evaluates the utility of word embeddings, generated by large language models (LLMs), for medical diagnosis by comparing the semantic proximity of symptoms to their eponymic disease embedding ("eponymic condition") and the mean o...

A dataset and benchmark for hospital course summarization with adapted large language models.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVE: Brief hospital course (BHC) summaries are clinical documents that summarize a patient's hospital stay. While large language models (LLMs) depict remarkable capabilities in automating real-world tasks, their capabilities for healthcare appl...

Analysis of eligibility criteria clusters based on large language models for clinical trial design.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVES: Clinical trials (CTs) are essential for improving patient care by evaluating new treatments' safety and efficacy. A key component in CT protocols is the study population defined by the eligibility criteria. This study aims to evaluate the...

ESCARGOT: an AI agent leveraging large language models, dynamic graph of thoughts, and biomedical knowledge graphs for enhanced reasoning.

Bioinformatics (Oxford, England)
MOTIVATION: LLMs like GPT-4, despite their advancements, often produce hallucinations and struggle with integrating external knowledge effectively. While Retrieval-Augmented Generation (RAG) attempts to address this by incorporating external informat...

Assessing Completeness of Clinical Histories Accompanying Imaging Orders Using Adapted Open-Source and Closed-Source Large Language Models.

Radiology
Background Incomplete clinical histories are a well-known problem in radiology. Previous dedicated quality improvement efforts focusing on reproducible assessments of the completeness of free-text clinical histories have relied on tedious manual anal...

Application of large language models in clinical record correction: a comprehensive study on various retraining methods.

Journal of the American Medical Informatics Association : JAMIA
OBJECTIVES: We evaluate the effectiveness of large language models (LLMs), specifically GPT-based (GPT-3.5 and GPT-4) and Llama-2 models (13B and 7B architectures), in autonomously assessing clinical records (CRs) to enhance medical education and dia...

Testing and Evaluation of Health Care Applications of Large Language Models: A Systematic Review.

JAMA
IMPORTANCE: Large language models (LLMs) can assist in various health care activities, but current evaluation approaches may not adequately identify the most useful application areas.

A survey analysis of the adoption of large language models among pathologists.

American journal of clinical pathology
OBJECTIVES: We sought to investigate the adoption and perception of large language model (LLM) applications among pathologists.

Making the most of Artificial Intelligence and Large Language Models to support collection development in health sciences libraries.

Journal of the Medical Library Association : JMLA
This project investigated the potential of generative AI models in aiding health sciences librarians with collection development. Researchers at Chapman University's Harry and Diane Rinker Health Science campus evaluated four generative AI models-Cha...

Evaluating a large language model's ability to answer clinicians' requests for evidence summaries.

Journal of the Medical Library Association : JMLA
OBJECTIVE: This study investigated the performance of a generative artificial intelligence (AI) tool using GPT-4 in answering clinical questions in comparison with medical librarians' gold-standard evidence syntheses.