AIMC Topic: Longitudinal Studies

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Predicting humoral responses to primary and booster SARS-CoV-2 mRNA vaccination in people living with HIV: a machine learning approach.

Journal of translational medicine
BACKGROUND: SARS-CoV-2 mRNA vaccines are highly immunogenic in people living with HIV (PLWH) on effective antiretroviral therapy (ART). However, whether viro-immunologic parameters or other factors affect immune responses to vaccination is debated. T...

Intensive longitudinal assessment following index trauma to predict development of PTSD using machine learning.

Journal of anxiety disorders
There are significant challenges to identifying which individuals require intervention following exposure to trauma, and a need for strategies to identify and provide individuals at risk for developing PTSD with timely interventions. The present stud...

Predicting dental caries outcomes in young adults using machine learning approach.

BMC oral health
OBJECTIVES: To predict the dental caries outcomes in young adults from a set of longitudinally-obtained predictor variables and identify the most important predictors using machine learning techniques.

Examining how gamers connect with their avatars to assess their anxiety: A novel artificial intelligence approach.

Acta psychologica
Research has supported that a gamer's attachment to their avatar can offer significant insights about their mental health, including anxiety. To assess this hypothesis, longitudinal data from 565 adult and adolescent participants (M = 29.3 years, SD ...

Predicting clinical outcomes of SARS-CoV-2 infection during the Omicron wave using machine learning.

PloS one
The Omicron SARS-CoV-2 variant continues to strain healthcare systems. Developing tools that facilitate the identification of patients at highest risk of adverse outcomes is a priority. The study objectives are to develop population-scale predictive ...

Prospective prediction of anxiety onset in the Canadian longitudinal study on aging (CLSA): A machine learning study.

Journal of affective disorders
BACKGROUND: Anxiety disorders are among the most common mental health disorders in the middle aged and older population. Because older individuals are more likely to have multiple comorbidities or increased frailty, the impact of anxiety disorders on...

The gut microbiome associates with phenotypic manifestations of post-acute COVID-19 syndrome.

Cell host & microbe
The mechanisms underlying the many phenotypic manifestations of post-acute COVID-19 syndrome (PACS) are poorly understood. Herein, we characterized the gut microbiome in heterogeneous cohorts of subjects with PACS and developed a multi-label machine ...