BACKGROUND: Diabetes mellitus has been shown to increase the risk of dementia, with diabetic patients demonstrating twice the dementia incidence rate of non-diabetic populations. We aimed to develop and validate a novel machine learning-based dementi...
This study utilized data from the 2020 wave of the China Health and Retirement Longitudinal Study database, selecting 4322 participants aged 60 and above as the study sample. Important predictors of depression in older adults with functional disabili...
BACKGROUND: Early diagnosis and treatment of mental illnesses is hampered by the lack of reliable markers. This study used machine learning models to uncover diagnostic and risk prediction markers for eating disorders (EDs), major depressive disorder...
In longitudinal observational studies with time-varying confounders, the generalized computation algorithm formula (g-formula) is a principled tool to estimate the average causal effect of a treatment regimen. However, the standard non-iterative g-fo...
Positron emission tomography (PET) imaging technology is widely used for diagnosing Alzheimer's disease (AD) in people with dementia. Although various computational methods have been proposed for diagnosis of AD using PET images, prediction of diseas...
BACKGROUND AND OBJECTIVES: Cortical lesions in multiple sclerosis (MS) severely affect cognition, but their longitudinal evolution and impact on specific cognitive functions remain understudied. This study investigates the evolution of function-speci...
Current care in multiple sclerosis (MS) primarily relies on infrequently obtained data such as magnetic resonance imaging, clinical laboratory tests or clinical history, resulting in subtle changes that may occur between visits being missed. Mobile t...
BACKGROUND: The incidence of cardiovascular metabolic diseases (CMD) continues to rise among middle-aged and elderly populations, affecting not only physical health but also significantly increasing the risk of depression. This study aims to construc...
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