For all cancer types, survivability rates vary widely across different stages of cancer. But survivability prediction models built in past were trained using examples of all stages together and were also evaluated on all stages together. In this work...
Statistical techniques such as propensity score matching and instrumental variable are commonly employed to "simulate" randomization and adjust for measured confounders in comparative effectiveness research. Despite such adjustments, the results of t...
Gleason grading of histological images is important in risk assessment and treatment planning for prostate cancer patients. Much research has been done in classifying small homogeneous cancer regions within histological images. However, semi-supervis...
De-identification of clinical notes is a special case of named entity recognition. Supervised machine-learning (ML) algorithms have achieved promising results for this task. However, ML-based de-identification systems often require annotating a large...
Models have been developed to predict stroke outcomes (e.g., mortality) in attempt to provide better guidance for stroke treatment. However, there is little work in developing classification models for the problem of unknown time-since-stroke (TSS), ...
There is growing interest in applying machine learning methods to Electronic Medical Records (EMR). Across different institutions, however, EMR quality can vary widely. This work investigated the impact of this disparity on the performance of three a...
Social media are important platforms for risk communication during public health crises. Effective dissemination of accurate, relevant, and up-to-date health information is important for the public to raise awareness and develop risk management strat...
Advanced regression and machine learning models can provide personalized risk predictions to support clinical decision-making. We aimed to understand whether modeling methods impact the tendency of calibration to deteriorate as patient populations sh...
Incidence of Acute Kidney Injury (AKI) has increased dramatically over the past two decades due to rising prevalence of comorbidities and broadening repertoire of nephrotoxic medications. Hospitalized patients with AKI are at higher risk for complica...
Free-text reports in electronic health records (EHRs) contain medically significant information - signs, symptoms, findings, diagnoses - recorded by clinicians during patient encounters. These reports contain rich clinical information which can be le...
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